Ewing PJ - Search Results

1

Identification and characterization of A-105972, an antineoplastic agent.

Wu-Wong JR, Alder JD, Alder L, Burns DJ, Han EK, Credo B, Tahir SK, Dayton BD, Ewing PJ, Chiou WJ. Wu-Wong JR, et al. Among authors: ewing pj. Cancer Res. 2001 Feb 15;61(4):1486-92. Cancer Res. 2001. PMID: 11245455

2

Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy.

O'Connor SJ, Barr KJ, Wang L, Sorensen BK, Tasker AS, Sham H, Ng SC, Cohen J, Devine E, Cherian S, Saeed B, Zhang H, Lee JY, Warner R, Tahir S, Kovar P, Ewing P, Alder J, Mitten M, Leal J, Marsh K, Bauch J, Hoffman DJ, Sebti SM, Rosenberg SH. O'Connor SJ, et al. J Med Chem. 1999 Sep 9;42(18):3701-10. doi: 10.1021/jm9901935. J Med Chem. 1999. PMID: 10479301

3

Model of Streptococcus pneumoniae meningitis in adult rats.

Strake JG, Mitten MJ, Ewing PJ, Alder JD. Strake JG, et al. Among authors: ewing pj. Lab Anim Sci. 1996 Oct;46(5):524-9. Lab Anim Sci. 1996. PMID: 8905585

4

Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies.

Alder JD, Ewing PJ, Mitten MJ, Oleksijew A, Tanaka SK. Alder JD, et al. Among authors: ewing pj. Am J Gastroenterol. 1996 Nov;91(11):2347-54. Am J Gastroenterol. 1996. PMID: 8931416

5

In vivo efficacy of ABT-255 against drug-sensitive and -resistant Mycobacterium tuberculosis strains.

Oleksijew A, Meulbroek J, Ewing P, Jarvis K, Mitten M, Paige L, Tovcimak A, Nukkula M, Chu D, Alder JD. Oleksijew A, et al. Antimicrob Agents Chemother. 1998 Oct;42(10):2674-7. doi: 10.1128/AAC.42.10.2674. Antimicrob Agents Chemother. 1998. PMID: 9756775 Free PMC article.

6

Dynamics of clarithromycin and azithromycin efficacies against experimental Haemophilus influenzae pulmonary infection.

Alder JD, Ewing PJ, Nilius AM, Mitten M, Tovcimak A, Oleksijew A, Jarvis K, Paige L, Tanaka SK. Alder JD, et al. Among authors: ewing pj. Antimicrob Agents Chemother. 1998 Sep;42(9):2385-90. doi: 10.1128/AAC.42.9.2385. Antimicrob Agents Chemother. 1998. PMID: 9736568 Free PMC article.

7

Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens.

Or YS, Clark RF, Wang S, Chu DT, Nilius AM, Flamm RK, Mitten M, Ewing P, Alder J, Ma Z. Or YS, et al. J Med Chem. 2000 Mar 23;43(6):1045-9. doi: 10.1021/jm990618n. J Med Chem. 2000. PMID: 10737737 No abstract available.

8

Efficacies of ABT-773, a new ketolide, against experimental bacterial infections.

Mitten MJ, Meulbroek J, Nukkala M, Paige L, Jarvis K, Oleksijew A, Tovcimak A, Hernandez L, Alder JD, Ewing P, Or YS, Ma Z, Nilius AM, Mollison K, Flamm RK. Mitten MJ, et al. Antimicrob Agents Chemother. 2001 Sep;45(9):2585-93. doi: 10.1128/AAC.45.9.2585-2593.2001. Antimicrob Agents Chemother. 2001. PMID: 11502533 Free PMC article.

9

Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens.

Ma Z, Clark RF, Brazzale A, Wang S, Rupp MJ, Li L, Griesgraber G, Zhang S, Yong H, Phan LT, Nemoto PA, Chu DT, Plattner JJ, Zhang X, Zhong P, Cao Z, Nilius AM, Shortridge VD, Flamm R, Mitten M, Meulbroek J, Ewing P, Alder J, Or YS. Ma Z, et al. J Med Chem. 2001 Nov 22;44(24):4137-56. doi: 10.1021/jm0102349. J Med Chem. 2001. PMID: 11708916

10

Discovery of a series of cyclohexylethylamine-containing protein farnesyltransferase inhibitors exhibiting potent cellular activity.

Henry KJ Jr, Wasicak J, Tasker AS, Cohen J, Ewing P, Mitten M, Larsen JJ, Kalvin DM, Swenson R, Ng SC, Saeed B, Cherian S, Sham H, Rosenberg SH. Henry KJ Jr, et al. J Med Chem. 1999 Nov 18;42(23):4844-52. doi: 10.1021/jm990335v. J Med Chem. 1999. PMID: 10579847

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