Downes CP - Search Results

1

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS. Hajduch E, et al. Among authors: downes cp. Diabetologia. 2001 Feb;44(2):173-83. doi: 10.1007/s001250051596. Diabetologia. 2001. PMID: 11270673

2

Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.

Batty IH, Fleming IN, Downes CP. Batty IH, et al. Among authors: downes cp. Biochem J. 2004 May 1;379(Pt 3):641-51. doi: 10.1042/BJ20031700. Biochem J. 2004. PMID: 14769130 Free PMC article.

3

Thrombin receptors modulate insulin-stimulated phosphatidylinositol 3,4,5-trisphosphate accumulation in 1321N1 astrocytoma cells.

Batty IH, Downes CP. Batty IH, et al. Among authors: downes cp. Biochem J. 1996 Jul 15;317 ( Pt 2)(Pt 2):347-51. doi: 10.1042/bj3170347. Biochem J. 1996. PMID: 8713057 Free PMC article.

4

Inositol phospholipid 3-kinase is activated by cellular stress but is not required for the stress-induced activation of glucose transport in L6 rat skeletal muscle cells.

McDowell HE, Walker T, Hajduch E, Christie G, Batty IH, Downes CP, Hundal HS. McDowell HE, et al. Among authors: downes cp. Eur J Biochem. 1997 Jul 1;247(1):306-13. doi: 10.1111/j.1432-1033.1997.00306.x. Eur J Biochem. 1997. PMID: 9249041 Free article.

5

Cross-talk between phospholipase C and phosphoinositide 3-kinase signalling pathways.

Batty IH, Hickinson DM, Downes CP. Batty IH, et al. Among authors: downes cp. Biochem Soc Trans. 1997 Nov;25(4):1132-7. doi: 10.1042/bst0251132. Biochem Soc Trans. 1997. PMID: 9449962 Review.

6

Serotonin (5-Hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle.

Hajduch E, Rencurel F, Balendran A, Batty IH, Downes CP, Hundal HS. Hajduch E, et al. Among authors: downes cp. J Biol Chem. 1999 May 7;274(19):13563-8. doi: 10.1074/jbc.274.19.13563. J Biol Chem. 1999. PMID: 10224126 Free article.

7

Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.

Tang X, Batty IH, Downes CP. Tang X, et al. Among authors: downes cp. J Biol Chem. 2002 Jan 4;277(1):338-44. doi: 10.1074/jbc.M108927200. Epub 2001 Nov 1. J Biol Chem. 2002. PMID: 11694521 Free article.

8

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP. Walker SM, et al. Among authors: downes cp. Biochem J. 2004 Apr 15;379(Pt 2):301-7. doi: 10.1042/BJ20031839. Biochem J. 2004. PMID: 14711368 Free PMC article.

9

Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation.

Hale BG, Batty IH, Downes CP, Randall RE. Hale BG, et al. Among authors: downes cp. J Biol Chem. 2008 Jan 18;283(3):1372-1380. doi: 10.1074/jbc.M708862200. Epub 2007 Nov 20. J Biol Chem. 2008. PMID: 18029356 Free article.

10

A novel, rapid, and highly sensitive mass assay for phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) and its application to measure insulin-stimulated PtdIns(3,4,5)P3 production in rat skeletal muscle in vivo.

van der Kaay J, Batty IH, Cross DA, Watt PW, Downes CP. van der Kaay J, et al. Among authors: downes cp. J Biol Chem. 1997 Feb 28;272(9):5477-81. doi: 10.1074/jbc.272.9.5477. J Biol Chem. 1997. PMID: 9038150 Free article.

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