Venkataramanan R - Search Results

1

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Venkataramanan R, Strom S, Thummel K, Boguski MS, Schuetz E. Kuehl P, et al. Among authors: venkataramanan r. Nat Genet. 2001 Apr;27(4):383-91. doi: 10.1038/86882. Nat Genet. 2001. PMID: 11279519

2

The use of human hepatocyte cultures to study the induction of cytochrome P-450.

Kostrubsky VE, Ramachandran V, Venkataramanan R, Dorko K, Esplen JE, Zhang S, Sinclair JF, Wrighton SA, Strom SC. Kostrubsky VE, et al. Among authors: venkataramanan r. Drug Metab Dispos. 1999 Aug;27(8):887-94. Drug Metab Dispos. 1999. PMID: 10421615

3

Milk thistle, a herbal supplement, decreases the activity of CYP3A4 and uridine diphosphoglucuronosyl transferase in human hepatocyte cultures.

Venkataramanan R, Ramachandran V, Komoroski BJ, Zhang S, Schiff PL, Strom SC. Venkataramanan R, et al. Drug Metab Dispos. 2000 Nov;28(11):1270-3. Drug Metab Dispos. 2000. PMID: 11038151

4

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD. Schuetz EG, et al. Among authors: venkataramanan r. J Biol Chem. 2001 Oct 19;276(42):39411-8. doi: 10.1074/jbc.M106340200. Epub 2001 Aug 16. J Biol Chem. 2001. PMID: 11509573 Free article.

5

PharmGKB update: II. CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5.

Schuetz EG, Relling MV, Kishi S, Yang W, Das S, Chen P, Cook EH, Rosner GL, Pui CH, Blanco JG, Edick MJ, Hancock ML, Winick NJ, Dervieux T, Amylon MD, Bash RO, Behm FG, Camitta BM, Raimondi SC, Goh BC, Lee SC, Wang LZ, Fan L, Guo JY, Lamba J, Lim R, Lim HL, Ong AB, Lee HS, Kuehl P, Zhang J, Lin Y, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Brimer C, Yasuda K, Venkataramanan R, Strom S, Thummel K, Boguski MS. Schuetz EG, et al. Among authors: venkataramanan r. Pharmacol Rev. 2004 Jun;56(2):159. doi: 10.1124/pr.56.2.1. Pharmacol Rev. 2004. PMID: 15169924 No abstract available.

6

In vitro and in vivo assessment of herb drug interactions.

Venkataramanan R, Komoroski B, Strom S. Venkataramanan R, et al. Life Sci. 2006 Mar 27;78(18):2105-15. doi: 10.1016/j.lfs.2005.12.021. Epub 2006 Jan 19. Life Sci. 2006. PMID: 16427092 Review.

7

MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.

Lamba J, Strom S, Venkataramanan R, Thummel KE, Lin YS, Liu W, Cheng C, Lamba V, Watkins PB, Schuetz E. Lamba J, et al. Among authors: venkataramanan r. Clin Pharmacol Ther. 2006 Apr;79(4):325-38. doi: 10.1016/j.clpt.2005.11.013. Epub 2006 Feb 20. Clin Pharmacol Ther. 2006. PMID: 16580901

8

Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.

Lamba J, Lamba V, Strom S, Venkataramanan R, Schuetz E. Lamba J, et al. Among authors: venkataramanan r. Drug Metab Dispos. 2008 Jan;36(1):169-81. doi: 10.1124/dmd.107.016600. Epub 2007 Oct 9. Drug Metab Dispos. 2008. PMID: 17925385

9

A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine.

Yasuda K, Ranade A, Venkataramanan R, Strom S, Chupka J, Ekins S, Schuetz E, Bachmann K. Yasuda K, et al. Among authors: venkataramanan r. Drug Metab Dispos. 2008 Aug;36(8):1689-97. doi: 10.1124/dmd.108.020701. Epub 2008 May 27. Drug Metab Dispos. 2008. PMID: 18505790 Free PMC article.

10

Effect of voriconazole and other azole antifungal agents on CYP3A activity and metabolism of tacrolimus in human liver microsomes.

Zhang S, Pillai VC, Mada SR, Strom S, Venkataramanan R. Zhang S, et al. Among authors: venkataramanan r. Xenobiotica. 2012 May;42(5):409-16. doi: 10.3109/00498254.2011.631224. Epub 2011 Nov 22. Xenobiotica. 2012. PMID: 22106961

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