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Elevated PC-1 content in cultured skin fibroblasts correlates with decreased in vivo and in vitro insulin action in nondiabetic subjects: evidence that PC-1 may be an intrinsic factor in impaired insulin receptor signaling.
Frittitta L, Spampinato D, Solini A, Nosadini R, Goldfine ID, Vigneri R, Trischitta V. Frittitta L, et al. Among authors: spampinato d. Diabetes. 1998 Jul;47(7):1095-100. doi: 10.2337/diabetes.47.7.1095. Diabetes. 1998. PMID: 9648833
High insulin levels do not influence PC-1 gene expression and protein content in human muscle tissue and hepatoma cells.
Frittitta L, Sbraccia P, Costanzo BV, Tassi V, D'Adamo M, Spampinato D, Ercolino T, Purrello F, Tamburrano G, Vigneri R, Trischitta V. Frittitta L, et al. Among authors: spampinato d, d adamo m. Diabetes Metab Res Rev. 2000 Jan-Feb;16(1):26-32. doi: 10.1002/(sici)1520-7560(200001/02)16:1<26::aid-dmrr78>3.0.co;2-n. Diabetes Metab Res Rev. 2000. PMID: 10707036
A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities.
Frittitta L, Ercolino T, Bozzali M, Argiolas A, Graci S, Santagati MG, Spampinato D, Di Paola R, Cisternino C, Tassi V, Vigneri R, Pizzuti A, Trischitta V. Frittitta L, et al. Among authors: spampinato d. Diabetes. 2001 Aug;50(8):1952-5. doi: 10.2337/diabetes.50.8.1952. Diabetes. 2001. PMID: 11473061
A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance.
Di Paola R, Frittitta L, Miscio G, Bozzali M, Baratta R, Centra M, Spampinato D, Santagati MG, Ercolino T, Cisternino C, Soccio T, Mastroianno S, Tassi V, Almgren P, Pizzuti A, Vigneri R, Trischitta V. Di Paola R, et al. Among authors: spampinato d. Am J Hum Genet. 2002 Mar;70(3):806-12. doi: 10.1086/339270. Epub 2002 Feb 6. Am J Hum Genet. 2002. PMID: 11833006 Free PMC article.
59 results