A PC-1 amino acid variant (K121Q) is associated with faster progression of renal disease in patients with type 1 diabetes and albuminuria.
De Cosmo S, Argiolas A, Miscio G, Thomas S, Piras GP, Trevisan R, Perin PC, Bacci S, Zucaro L, Margaglione M, Frittitta L, Pizzuti A, Tassi V, Viberti GC, Trischitta V.
De Cosmo S, et al. Among authors: trischitta v.
Diabetes. 2000 Mar;49(3):521-4. doi: 10.2337/diabetes.49.3.521.
Diabetes. 2000.
PMID: 10868979