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Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose.
Ma Y, Stern RJ, Scherman MS, Vissa VD, Yan W, Jones VC, Zhang F, Franzblau SG, Lewis WH, McNeil MR. Ma Y, et al. Among authors: jones vc. Antimicrob Agents Chemother. 2001 May;45(5):1407-16. doi: 10.1128/AAC.45.5.1407-1416.2001. Antimicrob Agents Chemother. 2001. PMID: 11302803 Free PMC article.
Expression, essentiality, and a microtiter plate assay for mycobacterial GlmU, the bifunctional glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase.
Zhang W, Jones VC, Scherman MS, Mahapatra S, Crick D, Bhamidi S, Xin Y, McNeil MR, Ma Y. Zhang W, et al. Among authors: jones vc. Int J Biochem Cell Biol. 2008;40(11):2560-71. doi: 10.1016/j.biocel.2008.05.003. Epub 2008 May 15. Int J Biochem Cell Biol. 2008. PMID: 18573680 Free PMC article.
Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC).
Sivendran S, Jones V, Sun D, Wang Y, Grzegorzewicz AE, Scherman MS, Napper AD, McCammon JA, Lee RE, Diamond SL, McNeil M. Sivendran S, et al. Bioorg Med Chem. 2010 Jan 15;18(2):896-908. doi: 10.1016/j.bmc.2009.11.033. Epub 2009 Nov 20. Bioorg Med Chem. 2010. PMID: 19969466 Free PMC article.
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