Nicoll-Griffith DA - Search Results

1

Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography-mass spectrometry.

Bateman KP, Castonguay G, Xu L, Rowland S, Nicoll-Griffith DA, Kelly N, Chan CC. Bateman KP, et al. J Chromatogr B Biomed Sci Appl. 2001 Apr 15;754(1):245-51. doi: 10.1016/s0378-4347(00)00612-5. J Chromatogr B Biomed Sci Appl. 2001. PMID: 11318421

2

Detection of covalent adducts to cytochrome P450 3A4 using liquid chromatography mass spectrometry.

Bateman KP, Baker J, Wilke M, Lee J, Leriche T, Seto C, Day S, Chauret N, Ouellet M, Nicoll-Griffith DA. Bateman KP, et al. Chem Res Toxicol. 2004 Oct;17(10):1356-61. doi: 10.1021/tx0498861. Chem Res Toxicol. 2004. PMID: 15487896

3

A strategy for identification of drug metabolites from dried blood spots using triple-quadrupole/linear ion trap hybrid mass spectrometry.

Mauriala T, Chauret N, Oballa R, Nicoll-Griffith DA, Bateman KP. Mauriala T, et al. Rapid Commun Mass Spectrom. 2005;19(14):1984-92. doi: 10.1002/rcm.2013. Rapid Commun Mass Spectrom. 2005. PMID: 15954171

4

MSE with mass defect filtering for in vitro and in vivo metabolite identification.

Bateman KP, Castro-Perez J, Wrona M, Shockcor JP, Yu K, Oballa R, Nicoll-Griffith DA. Bateman KP, et al. Rapid Commun Mass Spectrom. 2007;21(9):1485-96. doi: 10.1002/rcm.2996. Rapid Commun Mass Spectrom. 2007. PMID: 17394128

5

Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560.

Bateman KP, Trimble L, Chauret N, Silva J, Day S, Macdonald D, Dube D, Gallant M, Mastracchio A, Perrier H, Girard Y, Nicoll-Griffith D. Bateman KP, et al. J Mass Spectrom. 2006 Jun;41(6):771-80. doi: 10.1002/jms.1033. J Mass Spectrom. 2006. PMID: 16705670

6

High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry.

Wu J, Hughes CS, Picard P, Letarte S, Gaudreault M, Lévesque JF, Nicoll-Griffith DA, Bateman KP. Wu J, et al. Anal Chem. 2007 Jun 15;79(12):4657-65. doi: 10.1021/ac070221o. Epub 2007 May 12. Anal Chem. 2007. PMID: 17497828

7

The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes.

Chauret N, Dobbs B, Lackman RL, Bateman K, Nicoll-Griffith DA, Stresser DM, Ackermann JM, Turner SD, Miller VP, Crespi CL. Chauret N, et al. Drug Metab Dispos. 2001 Sep;29(9):1196-200. Drug Metab Dispos. 2001. PMID: 11502727

8

Oxidative bioactivation of the lactol prodrug of a lactone cyclooxygenase-2 inhibitor.

Nicoll-Griffith DA, Falgueyret JP, Silva JM, Morin PE, Trimble L, Chan CC, Clas S, Leger S, Wang Z, Yergey JA, Riendeau D. Nicoll-Griffith DA, et al. Drug Metab Dispos. 1999 Mar;27(3):403-9. Drug Metab Dispos. 1999. PMID: 10064573

9

2,3-Diarylcyclopentenones as orally active, highly selective cyclooxygenase-2 inhibitors.

Black WC, Brideau C, Chan CC, Charleson S, Chauret N, Claveau D, Ethier D, Gordon R, Greig G, Guay J, Hughes G, Jolicoeur P, Leblanc Y, Nicoll-Griffith D, Ouimet N, Riendeau D, Visco D, Wang Z, Xu L, Prasit P. Black WC, et al. J Med Chem. 1999 Apr 8;42(7):1274-81. doi: 10.1021/jm980642l. J Med Chem. 1999. PMID: 10197970

10

Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).

Sturino CF, O'Neill G, Lachance N, Boyd M, Berthelette C, Labelle M, Li L, Roy B, Scheigetz J, Tsou N, Aubin Y, Bateman KP, Chauret N, Day SH, Lévesque JF, Seto C, Silva JH, Trimble LA, Carriere MC, Denis D, Greig G, Kargman S, Lamontagne S, Mathieu MC, Sawyer N, Slipetz D, Abraham WM, Jones T, McAuliffe M, Piechuta H, Nicoll-Griffith DA, Wang Z, Zamboni R, Young RN, Metters KM. Sturino CF, et al. J Med Chem. 2007 Feb 22;50(4):794-806. doi: 10.1021/jm0603668. J Med Chem. 2007. PMID: 17300164

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