Dougherty TJ - Search Results

1

Synthesis, photophysical properties, tumor uptake, and preliminary in vivo photosensitizing efficacy of a homologous series of 3-(1'-alkyloxy)ethyl-3-devinylpurpurin-18-N-alkylimides with variable lipophilicity.

Zheng G, Potter WR, Camacho SH, Missert JR, Wang G, Bellnier DA, Henderson BW, Rodgers MA, Dougherty TJ, Pandey RK. Zheng G, et al. Among authors: dougherty tj. J Med Chem. 2001 May 10;44(10):1540-59. doi: 10.1021/jm0005510. J Med Chem. 2001. PMID: 11334564

2

Bacteriopurpurinimides: highly stable and potent photosensitizers for photodynamic therapy.

Chen Y, Graham A, Potter W, Morgan J, Vaughan L, Bellnier DA, Henderson BW, Oseroff A, Dougherty TJ, Pandey RK. Chen Y, et al. Among authors: dougherty tj. J Med Chem. 2002 Jan 17;45(2):255-8. doi: 10.1021/jm010400c. J Med Chem. 2002. PMID: 11784129

3

A first comparative study of purpurinimide-based fluorinated vs. nonfluorinated photosensitizers for photodynamic therapy.

Gryshuk AL, Graham A, Pandey SK, Potter WR, Missert JR, Oseroff A, Dougherty TJ, Pandey RK. Gryshuk AL, et al. Among authors: dougherty tj. Photochem Photobiol. 2002 Nov;76(5):555-9. doi: 10.1562/0031-8655(2002)076<0555:afcsop>2.0.co;2. Photochem Photobiol. 2002. PMID: 12462653

4

Synthesis, comparative photosensitizing efficacy, human serum albumin (site II) binding ability, and intracellular localization characteristics of novel benzobacteriochlorins derived from vic-dihydroxybacteriochlorins.

Li G, Graham A, Chen Y, Dobhal MP, Morgan J, Zheng G, Kozyrev A, Oseroff A, Dougherty TJ, Pandey RK. Li G, et al. Among authors: dougherty tj. J Med Chem. 2003 Dec 4;46(25):5349-59. doi: 10.1021/jm030341y. J Med Chem. 2003. PMID: 14640543

5

Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides.

Chen Y, Sumlin A, Morgan J, Gryshuk A, Oseroff A, Henderson BW, Dougherty TJ, Pandey RK. Chen Y, et al. Among authors: dougherty tj. J Med Chem. 2004 Sep 23;47(20):4814-7. doi: 10.1021/jm049630s. J Med Chem. 2004. PMID: 15369384

6

Methyl pyropheophorbide-a analogues: potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy.

Chen Y, Zheng X, Dobhal MP, Gryshuk A, Morgan J, Dougherty TJ, Oseroff A, Pandey RK. Chen Y, et al. Among authors: dougherty tj. J Med Chem. 2005 Jun 2;48(11):3692-5. doi: 10.1021/jm050039k. J Med Chem. 2005. PMID: 15916419

7

Purpurinimide carbohydrate conjugates: effect of the position of the carbohydrate moiety in photosensitizing efficacy.

Pandey SK, Zheng X, Morgan J, Missert JR, Liu TH, Shibata M, Bellnier DA, Oseroff AR, Henderson BW, Dougherty TJ, Pandey RK. Pandey SK, et al. Among authors: dougherty tj. Mol Pharm. 2007 May-Jun;4(3):448-64. doi: 10.1021/mp060135x. Epub 2007 Mar 21. Mol Pharm. 2007. PMID: 17373821

8

Alkyl ether analogs of chlorophyll-a derivatives: Part 1. Synthesis, photophysical properties and photodynamic efficacy.

Pandey RK, Sumlin AB, Constantine S, Aoudla M, Potter WR, Bellnier DA, Henderson BW, Rodgers MA, Smith KM, Dougherty TJ. Pandey RK, et al. Among authors: dougherty tj. Photochem Photobiol. 1996 Jul;64(1):194-204. doi: 10.1111/j.1751-1097.1996.tb02442.x. Photochem Photobiol. 1996. PMID: 8787014

9

Comparative in vivo sensitizing efficacy of porphyrin and chlorin dimers joined with ester, ether, carbon-carbon or amide bonds.

Pandey RK, Zheng G, Lee DA, Dougherty TJ, Smith KM. Pandey RK, et al. Among authors: dougherty tj. J Mol Recognit. 1996 Mar-Apr;9(2):118-22. doi: 10.1002/(SICI)1099-1352(199603)9:2%3C118::AID-JMR251%3E3.0.CO;2-8. J Mol Recognit. 1996. PMID: 8877802

10

Synthesis, photophysical properties, in vivo photosensitizing efficacy, and human serum albumin binding properties of some novel bacteriochlorins.

Pandey RK, Constantine S, Tsuchida T, Zheng G, Medforth CJ, Aoudia M, Kozyrev AN, Rodgers MA, Kato H, Smith KM, Dougherty TJ. Pandey RK, et al. Among authors: dougherty tj. J Med Chem. 1997 Aug 15;40(17):2770-9. doi: 10.1021/jm9702894. J Med Chem. 1997. PMID: 9276023

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