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Page 1
Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.
Ames RS, Lee D, Foley JJ, Jurewicz AJ, Tornetta MA, Bautsch W, Settmacher B, Klos A, Erhard KF, Cousins RD, Sulpizio AC, Hieble JP, McCafferty G, Ward KW, Adams JL, Bondinell WE, Underwood DC, Osborn RR, Badger AM, Sarau HM. Ames RS, et al. Among authors: underwood dc. J Immunol. 2001 May 15;166(10):6341-8. doi: 10.4049/jimmunol.166.10.6341. J Immunol. 2001. PMID: 11342658
Nonpeptide tachykinin receptor antagonists. III. SB 235375, a low central nervous system-penetrant, potent and selective neurokinin-3 receptor antagonist, inhibits citric acid-induced cough and airways hyper-reactivity in guinea pigs.
Hay DW, Giardina GA, Griswold DE, Underwood DC, Kotzer CJ, Bush B, Potts W, Sandhu P, Lundberg D, Foley JJ, Schmidt DB, Martin LD, Kilian D, Legos JJ, Barone FC, Luttmann MA, Grugni M, Raveglia LF, Sarau HM. Hay DW, et al. Among authors: underwood dc. J Pharmacol Exp Ther. 2002 Jan;300(1):314-23. doi: 10.1124/jpet.300.1.314. J Pharmacol Exp Ther. 2002. PMID: 11752131
In vitro and in vivo pharmacological characterization of SB 201993, an eicosanoid-like LTB4 receptor antagonist with anti-inflammatory activity.
Sarau HM, Foley JJ, Schmidt DB, Martin LD, Webb EF, Tzimas MN, Breton JJ, Chabot-Fletcher M, Underwood DC, Hay DW, Kingsbury WD, Chambers PA, Pendrak I, Jakas DR, Sathe GM, Van Horn S, Daines RA, Griswold DE. Sarau HM, et al. Among authors: underwood dc. Prostaglandins Leukot Essent Fatty Acids. 1999 Jul;61(1):55-64. doi: 10.1054/plef.1999.0074. Prostaglandins Leukot Essent Fatty Acids. 1999. PMID: 10477044
36 results