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Probing the aglycon binding site of a beta-glucosidase: a collection of C-1-modified 2,5-dideoxy-2,5-imino-D-mannitol derivatives and their structure-activity relationships as competitive inhibitors.
Wrodnigg TM, Diness F, Gruber C, Häusler H, Lundt I, Rupitz K, Steiner AJ, Stütz AE, Tarling CA, Withers SG, Wölfler H. Wrodnigg TM, et al. Among authors: withers sg. Bioorg Med Chem. 2004 Jul 1;12(13):3485-95. doi: 10.1016/j.bmc.2004.04.037. Bioorg Med Chem. 2004. PMID: 15186833
Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols.
Greimel P, Häusler H, Lundt I, Rupitz K, Stütz AE, Tarling CA, Withers SG, Wrodnigg TM. Greimel P, et al. Among authors: withers sg. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2067-70. doi: 10.1016/j.bmcl.2006.01.095. Epub 2006 Feb 14. Bioorg Med Chem Lett. 2006. PMID: 16481162
1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors.
Steiner AJ, Schitter G, Stütz AE, Wrodnigg TM, Tarling CA, Withers SG, Fantur K, Mahuran D, Paschke E, Tropak M. Steiner AJ, et al. Among authors: withers sg. Bioorg Med Chem. 2008 Dec 15;16(24):10216-20. doi: 10.1016/j.bmc.2008.10.054. Epub 2008 Oct 26. Bioorg Med Chem. 2008. PMID: 18996021 Free PMC article.
Synthesis and biological evaluation of novel biotin-iminoalditol conjugates.
Pototschnig G, De Csáky CM, Burke JR, Schitter G, Stütz AE, Tarling CA, Withers SG, Wrodnigg TM. Pototschnig G, et al. Among authors: withers sg. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4077-9. doi: 10.1016/j.bmcl.2010.05.084. Epub 2010 May 27. Bioorg Med Chem Lett. 2010. PMID: 20610152
482 results