Nettles JH - Search Results

1

Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition.

Judd DA, Nettles JH, Nevins N, Snyder JP, Liotta DC, Tang J, Ermolieff J, Schinazi RF, Hill CL. Judd DA, et al. Among authors: nettles jh. J Am Chem Soc. 2001 Feb 7;123(5):886-97. doi: 10.1021/ja001809e. J Am Chem Soc. 2001. PMID: 11456622

2

Stanton RA, Nettles JH, Schinazi RF. Stanton RA, et al. Among authors: nettles jh. J Mol Model. 2015 Nov;21(11):282. doi: 10.1007/s00894-015-2826-7. Epub 2015 Oct 8. J Mol Model. 2015. PMID: 26450349 Free PMC article.

3

The oxetane ring in taxol.

Wang M, Cornett B, Nettles J, Liotta DC, Snyder JP. Wang M, et al. J Org Chem. 2000 Feb 25;65(4):1059-68. doi: 10.1021/jo9916075. J Org Chem. 2000. PMID: 10814054

4

The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography.

Nettles JH, Li H, Cornett B, Krahn JM, Snyder JP, Downing KH. Nettles JH, et al. Science. 2004 Aug 6;305(5685):866-9. doi: 10.1126/science.1099190. Science. 2004. PMID: 15297674

5

Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors.

Stanton RA, Lu X, Detorio M, Montero C, Hammond ET, Ehteshami M, Domaoal RA, Nettles JH, Feraud M, Schinazi RF. Stanton RA, et al. Among authors: nettles jh. Bioorg Med Chem Lett. 2016 Aug 15;26(16):4101-5. doi: 10.1016/j.bmcl.2016.06.065. Epub 2016 Jun 25. Bioorg Med Chem Lett. 2016. PMID: 27390064 Free PMC article.

6

Comparative analysis of in vitro processivity of HIV-1 reverse transcriptases containing mutations 65R, 74V, 184V and 65R+74V.

Sharma PL, Nettles JH, Feldman A, Rapp K, Schinazi RF. Sharma PL, et al. Among authors: nettles jh. Antiviral Res. 2009 Sep;83(3):317-23. doi: 10.1016/j.antiviral.2009.06.002. Epub 2009 Jun 23. Antiviral Res. 2009. PMID: 19555722 Free PMC article.

7

The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density.

Snyder JP, Nettles JH, Cornett B, Downing KH, Nogales E. Snyder JP, et al. Among authors: nettles jh. Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5312-6. doi: 10.1073/pnas.051309398. Epub 2001 Apr 17. Proc Natl Acad Sci U S A. 2001. PMID: 11309480 Free PMC article.

8

Microtubule-interacting drugs for cancer treatment.

Checchi PM, Nettles JH, Zhou J, Snyder JP, Joshi HC. Checchi PM, et al. Among authors: nettles jh. Trends Pharmacol Sci. 2003 Jul;24(7):361-5. doi: 10.1016/S0165-6147(03)00161-5. Trends Pharmacol Sci. 2003. PMID: 12871669 Review. No abstract available.

9

Asymmetric binding to NS5A by daclatasvir (BMS-790052) and analogs suggests two novel modes of HCV inhibition.

Nettles JH, Stanton RA, Broyde J, Amblard F, Zhang H, Zhou L, Shi J, McBrayer TR, Whitaker T, Coats SJ, Kohler JJ, Schinazi RF. Nettles JH, et al. J Med Chem. 2014 Dec 11;57(23):10031-43. doi: 10.1021/jm501291c. Epub 2014 Nov 3. J Med Chem. 2014. PMID: 25365735 Free PMC article.

10

Synthesis and evaluation of non-dimeric HCV NS5A inhibitors.

Amblard F, Zhang H, Zhou L, Shi J, Bobeck DR, Nettles JH, Chavre S, McBrayer TR, Tharnish P, Whitaker T, Coats SJ, Schinazi RF. Amblard F, et al. Among authors: nettles jh. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2031-4. doi: 10.1016/j.bmcl.2013.02.023. Epub 2013 Feb 13. Bioorg Med Chem Lett. 2013. PMID: 23466233 Free PMC article.

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