Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins.
Lotersztajn S, Pavoine C, Brechler V, Roche B, Dufour M, Le-Nguyen D, Bataille D, Pecker F.
Lotersztajn S, et al.
J Biol Chem. 1990 Jun 15;265(17):9876-80.
J Biol Chem. 1990.
PMID: 2141022
Free article.
Treatment of rats with cholera toxin resulted in a 70% increase in the basal activity of the Ca2+ pump, a loss of sensitivity to GTP gamma S and to the biphasic regulation by glucagon-(19-29). Treatment with pertussis toxin did not affect the response of the Ca2+ pump to G …
Treatment of rats with cholera toxin resulted in a 70% increase in the basal activity of the Ca2+ pump, a loss of sensitivity to GTP gamma …