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Role of gamma-aminobutyric acid type A (GABAA) receptor subtypes in acute benzodiazepine physical dependence-like effects: evidence from squirrel monkeys responding under a schedule of food presentation.
Fischer BD, Teixeira LP, van Linn ML, Namjoshi OA, Cook JM, Rowlett JK. Fischer BD, et al. Among authors: cook jm. Psychopharmacology (Berl). 2013 May;227(2):347-54. doi: 10.1007/s00213-013-2975-2. Epub 2013 Jan 26. Psychopharmacology (Berl). 2013. PMID: 23354533 Free PMC article.
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423) at wild type and recombinant GABAA receptors.
Cox ED, Diaz-Arauzo H, Huang Q, Reddy MS, Ma C, Harris B, McKernan R, Skolnick P, Cook JM. Cox ED, et al. Among authors: cook jm. J Med Chem. 1998 Jul 2;41(14):2537-52. doi: 10.1021/jm970460b. J Med Chem. 1998. PMID: 9651158
Studies of molecular pharmacophore/receptor models for GABAA/benzodiazepine receptor subtypes: binding affinities of substituted beta-carbolines at recombinant alpha x beta 3 gamma 2 subtypes and quantitative structure-activity relationship studies via a comparative molecular field analysis.
Huang Q, Cox ED, Gan T, Ma C, Bennett DW, McKernan RM, Cook JM. Huang Q, et al. Among authors: cook jm. Drug Des Discov. 1999 Jul;16(1):55-76. Drug Des Discov. 1999. PMID: 10466057
628 results