Fairchild CR - Search Results

1

Synthesis and biological activity of novel epothilone aziridines.

Regueiro-Ren A, Borzilleri RM, Zheng X, Kim SH, Johnson JA, Fairchild CR, Lee FY, Long BH, Vite GD. Regueiro-Ren A, et al. Among authors: fairchild cr. Org Lett. 2001 Aug 23;3(17):2693-6. doi: 10.1021/ol016273w. Org Lett. 2001. PMID: 11506611

2

Synthesis and biological activity of macrocyclic taxane analogues.

Tarrant JG, Cook D, Fairchild C, Kadow JF, Long BH, Rose WC, Vyas D. Tarrant JG, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2555-8. doi: 10.1016/j.bmcl.2004.02.086. Bioorg Med Chem Lett. 2004. PMID: 15109650

3

SAR and pH stability of cyano-substituted epothilones.

Regueiro-Ren A, Leavitt K, Kim SH, Höfle G, Kiffe M, Gougoutas JZ, DiMarco JD, Lee FY, Fairchild CR, Long BH, Vite GD. Regueiro-Ren A, et al. Among authors: fairchild cr. Org Lett. 2002 Oct 31;4(22):3815-8. doi: 10.1021/ol026589j. Org Lett. 2002. PMID: 12599466

4

BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.

Lee FY, Borzilleri R, Fairchild CR, Kim SH, Long BH, Reventos-Suarez C, Vite GD, Rose WC, Kramer RA. Lee FY, et al. Among authors: fairchild cr. Clin Cancer Res. 2001 May;7(5):1429-37. Clin Cancer Res. 2001. PMID: 11350914

5

Synthesis and biological evaluation of novel C-4 aziridine-bearing paclitaxel (taxol) analogs.

Chen SH, Fairchild C, Long BH. Chen SH, et al. J Med Chem. 1995 Jun 9;38(12):2263-7. doi: 10.1021/jm00012a029. J Med Chem. 1995. PMID: 7783160

6

Synthesis, structure proof, and biological activity of epothilone cyclopropanes.

Johnson J, Kim SH, Bifano M, DiMarco J, Fairchild C, Gougoutas J, Lee F, Long B, Tokarski J, Vite G. Johnson J, et al. Org Lett. 2000 Jun 1;2(11):1537-40. doi: 10.1021/ol0058240. Org Lett. 2000. PMID: 10841473

7

Structure-activity relationships study at the 3'-N position of paclitaxel. Part 2: synthesis and biological evaluation of 3'-N-thiourea- and 3'-N-thiocarbamate-bearing paclitaxel analogues.

Xue M, Long BH, Fairchild C, Johnston K, Rose WC, Kadow JF, Vyas DM, Chen SH. Xue M, et al. Bioorg Med Chem Lett. 2000 Jun 19;10(12):1327-31. doi: 10.1016/s0960-894x(00)00242-0. Bioorg Med Chem Lett. 2000. PMID: 10890157

8

Synthesis of 7beta-sulfur analogues of paclitaxel utilizing a novel epimerization of the 7alpha-thiol group.

Mastalerz H, Zhang G, Kadow J, Fairchild C, Long B, Vyas DM. Mastalerz H, et al. Org Lett. 2001 May 31;3(11):1613-5. doi: 10.1021/ol015727m. Org Lett. 2001. PMID: 11405668

9

Synthesis and Biological Evaluation of 1-Deoxypaclitaxel Analogues.

Kingston DG, Chordia MD, Jagtap PG, Liang J, Shen YC, Long BH, Fairchild CR, Johnston KA. Kingston DG, et al. Among authors: fairchild cr. J Org Chem. 1999 Mar 19;64(6):1814-1822. doi: 10.1021/jo981406l. J Org Chem. 1999. PMID: 11674269

10

Novel 3',6'-anhydro and N12,N13-bridged glycosylated fluoroindolo[2,3-a]carbazoles as topoisomerase I inhibitors. Fluorine as a leaving group from sp3 carbon.

Saulnier MG, Langley DR, Frennesson DB, Long BH, Huang S, Gao Q, Wu D, Fairchild CR, Ruediger E, Zimmermann K, St Laurent DR, Balasubramanian BN, Vyas DM. Saulnier MG, et al. Among authors: fairchild cr. Org Lett. 2005 Mar 31;7(7):1271-4. doi: 10.1021/ol050013n. Org Lett. 2005. PMID: 15787484

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