Dunne A - Search Results

1

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA. Fitzgerald KA, et al. Among authors: dunne a. Nature. 2001 Sep 6;413(6851):78-83. doi: 10.1038/35092578. Nature. 2001. PMID: 11544529

2

The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense.

Dunne A, O'Neill LA. Dunne A, et al. Sci STKE. 2003 Feb 25;2003(171):re3. doi: 10.1126/stke.2003.171.re3. Sci STKE. 2003. PMID: 12606705 Review.

3

Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors.

O'Neill LA, Dunne A, Edjeback M, Gray P, Jefferies C, Wietek C. O'Neill LA, et al. Among authors: dunne a. J Endotoxin Res. 2003;9(1):55-9. doi: 10.1179/096805103125001351. J Endotoxin Res. 2003. PMID: 12691620 Review.

4

Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.

Jefferies CA, Doyle S, Brunner C, Dunne A, Brint E, Wietek C, Walch E, Wirth T, O'Neill LA. Jefferies CA, et al. Among authors: dunne a. J Biol Chem. 2003 Jul 11;278(28):26258-64. doi: 10.1074/jbc.M301484200. Epub 2003 Apr 30. J Biol Chem. 2003. PMID: 12724322 Free article.

5

Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.

Dunne A, Ejdeback M, Ludidi PL, O'Neill LA, Gay NJ. Dunne A, et al. J Biol Chem. 2003 Oct 17;278(42):41443-51. doi: 10.1074/jbc.M301742200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888566 Free article.

6

ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance.

Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O'Neill LA, Liew FY. Brint EK, et al. Among authors: dunne a. Nat Immunol. 2004 Apr;5(4):373-9. doi: 10.1038/ni1050. Epub 2004 Mar 7. Nat Immunol. 2004. PMID: 15004556 Free article.

7

Adaptor usage and Toll-like receptor signaling specificity.

Dunne A, O'Neill LA. Dunne A, et al. FEBS Lett. 2005 Jun 13;579(15):3330-5. doi: 10.1016/j.febslet.2005.04.024. Epub 2005 Apr 26. FEBS Lett. 2005. PMID: 15876435 Free article. Review.

8

New insights into the post-translational modification of Toll-like receptor signaling molecules.

Dunne A, O'Neill L. Dunne A, et al. J Endotoxin Res. 2005;11(6):325-32. doi: 10.1179/096805105X58742. J Endotoxin Res. 2005. PMID: 16303087 Review.

9

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Gray P, Dunne A, Brikos C, Jefferies CA, Doyle SL, O'Neill LA. Gray P, et al. Among authors: dunne a. J Biol Chem. 2006 Apr 14;281(15):10489-95. doi: 10.1074/jbc.M508892200. Epub 2006 Jan 26. J Biol Chem. 2006. PMID: 16439361 Free article.

10

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.

Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, Marsh K, Berkley JA, O'Neill LA, Hill AV. Khor CC, et al. Among authors: dunne a. Nat Genet. 2007 Apr;39(4):523-8. doi: 10.1038/ng1976. Epub 2007 Feb 25. Nat Genet. 2007. PMID: 17322885 Free PMC article.

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