Holman TR - Search Results

1

Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors.

Carroll J, Jonsson EN, Ebel R, Hartman MS, Holman TR, Crews P. Carroll J, et al. Among authors: holman tr. J Org Chem. 2001 Oct 19;66(21):6847-51. doi: 10.1021/jo015784t. J Org Chem. 2001. PMID: 11597201

2

Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase.

Mogul R, Johansen E, Holman TR. Mogul R, et al. Among authors: holman tr. Biochemistry. 2000 Apr 25;39(16):4801-7. doi: 10.1021/bi992805t. Biochemistry. 2000. PMID: 10769137

3

Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.

Whitman S, Gezginci M, Timmermann BN, Holman TR. Whitman S, et al. Among authors: holman tr. J Med Chem. 2002 Jun 6;45(12):2659-61. doi: 10.1021/jm0201262. J Med Chem. 2002. PMID: 12036375

4

Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR. Amagata T, et al. Among authors: holman tr. J Nat Prod. 2003 Feb;66(2):230-5. doi: 10.1021/np020462l. J Nat Prod. 2003. PMID: 12608855

5

Stopped-flow kinetic investigations of the activation of soybean lipoxygenase-1 and the influence of inhibitors on the allosteric site.

Ruddat VC, Whitman S, Holman TR, Bernasconi CF. Ruddat VC, et al. Among authors: holman tr. Biochemistry. 2003 Apr 15;42(14):4172-8. doi: 10.1021/bi020698o. Biochemistry. 2003. PMID: 12680771

6

Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.

Segraves EN, Holman TR. Segraves EN, et al. Among authors: holman tr. Biochemistry. 2003 May 13;42(18):5236-43. doi: 10.1021/bi0273462. Biochemistry. 2003. PMID: 12731864

7

Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Segraves EN, et al. Among authors: holman tr. J Med Chem. 2004 Jul 29;47(16):4060-5. doi: 10.1021/jm049872s. J Med Chem. 2004. PMID: 15267244

8

An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge.

Gautschi JT, Whitman S, Holman TR, Crews P. Gautschi JT, et al. Among authors: holman tr. J Nat Prod. 2004 Aug;67(8):1256-61. doi: 10.1021/np0340495. J Nat Prod. 2004. PMID: 15332838

9

Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors.

Cichewicz RH, Kenyon VA, Whitman S, Morales NM, Arguello JF, Holman TR, Crews P. Cichewicz RH, et al. Among authors: holman tr. J Am Chem Soc. 2004 Nov 17;126(45):14910-20. doi: 10.1021/ja046082z. J Am Chem Soc. 2004. PMID: 15535718

10

A Re(V)-catalyzed C-N bond-forming route to human lipoxygenase inhibitors.

Ohri RV, Radosevich AT, Hrovat KJ, Musich C, Huang D, Holman TR, Toste FD. Ohri RV, et al. Among authors: holman tr. Org Lett. 2005 Jun 9;7(12):2501-4. doi: 10.1021/ol050897a. Org Lett. 2005. PMID: 15932233

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