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Synthesis of 9-O-substituted derivatives of 9-hydroxy-5, 6-dimethyl-6H-pyrido[4,3-b]carbazole-1-carboxylic acid (2-(dimethylamino)ethyl)amide and their 10- and 11-methyl analogues with improved antitumor activity.
Guillonneau C, PierréA, Charton Y, Guilbaud N, Kraus-Berthier L, Léonce S, Michel A, Bisagni E, Atassi G. Guillonneau C, et al. Among authors: atassi g. J Med Chem. 1999 Jun 17;42(12):2191-203. doi: 10.1021/jm981093m. J Med Chem. 1999. PMID: 10377224
Design, synthesis and biological activity of 7-O-(4-O-acetyl-3-iodo-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl) daunomycinone and 7-O-(3-chloro-2,3,6-trideoxy-4-O-propanoyl-alpha-L-lyxo- hexopyranosyl)daunomycinone.
Aligiannis N, Pouli N, Marakos P, Mitaku S, Skaltsounis AL, Leonce S, Pierre A, Atassi G. Aligiannis N, et al. Among authors: atassi g. Chem Pharm Bull (Tokyo). 2000 Jan;48(1):150-3. doi: 10.1248/cpb.48.150. Chem Pharm Bull (Tokyo). 2000. PMID: 10705494
202 results