Wells RG - Search Results

1

Betaglycan inhibits TGF-beta signaling by preventing type I-type II receptor complex formation. Glycosaminoglycan modifications alter betaglycan function.

Eickelberg O, Centrella M, Reiss M, Kashgarian M, Wells RG. Eickelberg O, et al. Among authors: wells rg. J Biol Chem. 2002 Jan 4;277(1):823-9. doi: 10.1074/jbc.M105110200. Epub 2001 Oct 19. J Biol Chem. 2002. PMID: 11668175 Free article.

2

Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent.

Liu C, Gaça MD, Swenson ES, Vellucci VF, Reiss M, Wells RG. Liu C, et al. Among authors: wells rg. J Biol Chem. 2003 Mar 28;278(13):11721-8. doi: 10.1074/jbc.M207728200. Epub 2003 Jan 22. J Biol Chem. 2003. PMID: 12547835 Free article.

3

Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization.

Uemura M, Swenson ES, Gaça MD, Giordano FJ, Reiss M, Wells RG. Uemura M, et al. Among authors: wells rg. Mol Biol Cell. 2005 Sep;16(9):4214-24. doi: 10.1091/mbc.e05-02-0149. Epub 2005 Jun 29. Mol Biol Cell. 2005. PMID: 15987742 Free PMC article.

4

Repetitive exposure to TGF-beta suppresses TGF-beta type I receptor expression by differentiated osteoblasts.

Kim KK, Ji C, Chang W, Wells RG, Gundberg CM, McCarthy TL, Centrella M. Kim KK, et al. Among authors: wells rg. Gene. 2006 Sep 1;379:175-84. doi: 10.1016/j.gene.2006.05.005. Epub 2006 May 19. Gene. 2006. PMID: 16806744

5

The type III TGF-β receptor betaglycan transmembrane-cytoplasmic domain fragment is stable after ectodomain cleavage and is a substrate of the intramembrane protease γ-secretase.

Blair CR, Stone JB, Wells RG. Blair CR, et al. Among authors: wells rg. Biochim Biophys Acta. 2011 Feb;1813(2):332-9. doi: 10.1016/j.bbamcr.2010.12.005. Epub 2010 Dec 15. Biochim Biophys Acta. 2011. PMID: 21167215 Free PMC article.

6

Autocrine release of TGF-beta by portal fibroblasts regulates cell growth.

Wells RG, Kruglov E, Dranoff JA. Wells RG, et al. FEBS Lett. 2004 Feb 13;559(1-3):107-10. doi: 10.1016/S0014-5793(04)00037-7. FEBS Lett. 2004. PMID: 14960316 Free article.

7

Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells.

Dranoff JA, Ogawa M, Kruglov EA, Gaça MD, Sévigny J, Robson SC, Wells RG. Dranoff JA, et al. Among authors: wells rg. Am J Physiol Gastrointest Liver Physiol. 2004 Aug;287(2):G417-24. doi: 10.1152/ajpgi.00294.2003. Epub 2004 Feb 5. Am J Physiol Gastrointest Liver Physiol. 2004. PMID: 14764443 Free PMC article.

8

Portal fibroblasts: Underappreciated mediators of biliary fibrosis.

Dranoff JA, Wells RG. Dranoff JA, et al. Among authors: wells rg. Hepatology. 2010 Apr;51(4):1438-44. doi: 10.1002/hep.23405. Hepatology. 2010. PMID: 20209607 Free PMC article. Review.

9

Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet.

Wells RG, Discher DE. Wells RG, et al. Sci Signal. 2008 Mar 11;1(10):pe13. doi: 10.1126/stke.110pe13. Sci Signal. 2008. PMID: 18334714 Free PMC article. Review.

10

Cysteine-rich domain of type III collagen N-propeptide inhibits fibroblast activation by attenuating TGFβ signaling.

Brisson BK, Stewart DC, Burgwin C, Chenoweth D, Wells RG, Adams SL, Volk SW. Brisson BK, et al. Among authors: wells rg. Matrix Biol. 2022 May;109:19-33. doi: 10.1016/j.matbio.2022.03.004. Epub 2022 Mar 24. Matrix Biol. 2022. PMID: 35339637 Free PMC article.

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