Enyedy IJ - Search Results

1

Iridals are a novel class of ligands for phorbol ester receptors with modest selectivity for the RasGRP receptor subfamily.

Shao L, Lewin NE, Lorenzo PS, Hu Z, Enyedy IJ, Garfield SH, Stone JC, Marner FJ, Blumberg PM, Wang S. Shao L, et al. Among authors: enyedy ij. J Med Chem. 2001 Nov 8;44(23):3872-80. doi: 10.1021/jm010258f. J Med Chem. 2001. PMID: 11689073

2

Structural basis of RasGRP binding to high-affinity PKC ligands.

Rong SB, Enyedy IJ, Qiao L, Zhao L, Ma D, Pearce LL, Lorenzo PS, Stone JC, Blumberg PM, Wang S, Kozikowski AP. Rong SB, et al. Among authors: enyedy ij. J Med Chem. 2002 Feb 14;45(4):853-60. doi: 10.1021/jm010422z. J Med Chem. 2002. PMID: 11831896

3

Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.

Pak Y, Enyedy IJ, Varady J, Kung JW, Lorenzo PS, Blumberg PM, Wang S. Pak Y, et al. Among authors: enyedy ij. J Med Chem. 2001 May 24;44(11):1690-701. doi: 10.1021/jm000488e. J Med Chem. 2001. PMID: 11356104

4

Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.

Enyedy IJ, Wang J, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1775-8. doi: 10.1016/s0960-894x(02)00243-3. Bioorg Med Chem Lett. 2002. PMID: 12067559

5

Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides.

Rong SB, Hu Y, Enyedy I, Powis G, Meuillet EJ, Wu X, Wang R, Wang S, Kozikowski AP. Rong SB, et al. J Med Chem. 2001 Mar 15;44(6):898-908. doi: 10.1021/jm000493i. J Med Chem. 2001. PMID: 11300871

6

Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase.

Enyedy IJ, Lee SL, Kuo AH, Dickson RB, Lin CY, Wang S. Enyedy IJ, et al. J Med Chem. 2001 Apr 26;44(9):1349-55. doi: 10.1021/jm000395x. J Med Chem. 2001. PMID: 11311057

7

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.

Enyedy IJ, Ling Y, Nacro K, Tomita Y, Wu X, Cao Y, Guo R, Li B, Zhu X, Huang Y, Long YQ, Roller PP, Yang D, Wang S. Enyedy IJ, et al. J Med Chem. 2001 Dec 6;44(25):4313-24. doi: 10.1021/jm010016f. J Med Chem. 2001. PMID: 11728179

8

Pharmacophore-based discovery of substituted pyridines as novel dopamine transporter inhibitors.

Enyedy IJ, Sakamuri S, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Bioorg Med Chem Lett. 2003 Feb 10;13(3):513-7. doi: 10.1016/s0960-894x(02)00943-5. Bioorg Med Chem Lett. 2003. PMID: 12565962

9

Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationships, and behavioral pharmacological studies.

Wang S, Sakamuri S, Enyedy IJ, Kozikowski AP, Deschaux O, Bandyopadhyay BC, Tella SR, Zaman WA, Johnson KM. Wang S, et al. Among authors: enyedy ij. J Med Chem. 2000 Feb 10;43(3):351-60. doi: 10.1021/jm990516x. J Med Chem. 2000. PMID: 10669562

10

Pharmacophore-based discovery, synthesis, and biological evaluation of 4-phenyl-1-arylalkyl piperidines as dopamine transporter inhibitors.

Sakamuri S, Enyedy IJ, Kozikowski AP, Zaman WA, Johnson KM, Wang S. Sakamuri S, et al. Among authors: enyedy ij. Bioorg Med Chem Lett. 2001 Feb 26;11(4):495-500. doi: 10.1016/s0960-894x(00)00703-4. Bioorg Med Chem Lett. 2001. PMID: 11229756

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