Brown GD - Search Results

1

Two routes to [11C-carbonyl]organo-isocyanates utilizing [11C]phosgene ([11C]organo-isocyanates from [11C]phosgene).

Brown GD, Henderson D, Steel C, Luthra S, Price PM, Brady F. Brown GD, et al. Nucl Med Biol. 2001 Nov;28(8):991-8. doi: 10.1016/s0969-8051(01)00263-3. Nucl Med Biol. 2001. PMID: 11711319

2

Antitumor imidazotetrazines. 40. Radiosyntheses of [4-11C-carbonyl]- and [3-N-11C-methyl]-8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (temozolomide) for positron emission tomography (PET) studies.

Brown GD, Luthra SK, Brock CS, Stevens MF, Price PM, Brady F. Brown GD, et al. J Med Chem. 2002 Dec 5;45(25):5448-57. doi: 10.1021/jm020921f. J Med Chem. 2002. PMID: 12459013

3

Carbon-11 labelling of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and determination of plasma metabolites in man.

Brady F, Luthra SK, Brown G, Osman S, Harte RJ, Denny WA, Baguley BC, Jones T, Price PM. Brady F, et al. Appl Radiat Isot. 1997 Apr;48(4):487-92. doi: 10.1016/s0969-8043(96)00294-1. Appl Radiat Isot. 1997. PMID: 9106990 Clinical Trial.

4

An automated radiosynthesis of 2-[11C]thymidine using anhydrous [11C]urea derived from [11C]phosgene.

Steel CJ, Brady F, Luthra SK, Brown G, Khan I, Poole KG, Sergis A, Jones T, Price PM. Steel CJ, et al. Appl Radiat Isot. 1999 Oct;51(4):377-88. doi: 10.1016/s0969-8043(99)00051-2. Appl Radiat Isot. 1999. PMID: 10464914

5

Comparative biodistribution and metabolism of carbon-11-labeled N-[2-(dimethylamino)ethyl]acridine-4-carboxamide and DNA-intercalating analogues.

Osman S, Rowlinson-Busza G, Luthra SK, Aboagye EO, Brown GD, Brady F, Myers R, Gamage SA, Denny WA, Baguley BC, Price PM. Osman S, et al. Among authors: brown gd. Cancer Res. 2001 Apr 1;61(7):2935-44. Cancer Res. 2001. PMID: 11306471

6

Radiolabelled tracers and anticancer drugs for assessment of therapeutic efficacy using PET.

Brady F, Luthra SK, Brown GD, Osman S, Aboagye E, Saleem A, Price PM. Brady F, et al. Among authors: brown gd. Curr Pharm Des. 2001 Dec;7(18):1863-92. doi: 10.2174/1381612013396907. Curr Pharm Des. 2001. PMID: 11772355 Review.

7

Studies on the metabolism of the novel antitumor agent [N-methyl-11C]N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in rats and humans prior to phase I clinical trials.

Osman S, Luthra SK, Brady F, Hume SP, Brown G, Harte RJ, Matthews JC, Denny WA, Baguley BC, Jones T, Price PM. Osman S, et al. Cancer Res. 1997 Jun 1;57(11):2172-80. Cancer Res. 1997. PMID: 9187117 Clinical Trial.

8

Metabolic activation of temozolomide measured in vivo using positron emission tomography.

Saleem A, Brown GD, Brady F, Aboagye EO, Osman S, Luthra SK, Ranicar AS, Brock CS, Stevens MF, Newlands E, Jones T, Price P. Saleem A, et al. Among authors: brown gd. Cancer Res. 2003 May 15;63(10):2409-15. Cancer Res. 2003. PMID: 12750260

9

Pharmacokinetic evaluation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide in patients by positron emission tomography.

Saleem A, Harte RJ, Matthews JC, Osman S, Brady F, Luthra SK, Brown GD, Bleehen N, Connors T, Jones T, Price PM, Aboagye EO. Saleem A, et al. Among authors: brown gd. J Clin Oncol. 2001 Mar 1;19(5):1421-9. doi: 10.1200/JCO.2001.19.5.1421. J Clin Oncol. 2001. PMID: 11230487 Clinical Trial.

10

In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography.

Barthel H, Wilson H, Collingridge DR, Brown G, Osman S, Luthra SK, Brady F, Workman P, Price PM, Aboagye EO. Barthel H, et al. Br J Cancer. 2004 Jun 1;90(11):2232-42. doi: 10.1038/sj.bjc.6601862. Br J Cancer. 2004. PMID: 15150578 Free PMC article.

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