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Mimotopes of the hyper variable region 1 of the hepatitis C virus induce cross-reactive antibodies directed against discontinuous epitopes.
Roccasecca R, Folgori A, Ercole BB, Puntoriero G, Lahm A, Zucchelli S, Tafi R, Pezzanera M, Galfre G, Tramontano A, Mondelli MU, Pessi A, Nicosia A, Cortese R, Meola A. Roccasecca R, et al. Among authors: lahm a. Mol Immunol. 2001 Dec;38(6):485-92. doi: 10.1016/s0161-5890(01)00084-0. Mol Immunol. 2001. PMID: 11741698
Towards a solution for hepatitis C virus hypervariability: mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants.
Puntoriero G, Meola A, Lahm A, Zucchelli S, Ercole BB, Tafi R, Pezzanera M, Mondelli MU, Cortese R, Tramontano A, Galfre' G, Nicosia A. Puntoriero G, et al. Among authors: lahm a. EMBO J. 1998 Jul 1;17(13):3521-33. doi: 10.1093/emboj/17.13.3521. EMBO J. 1998. PMID: 9649423 Free PMC article.
A model for the hepatitis C virus envelope glycoprotein E2.
Yagnik AT, Lahm A, Meola A, Roccasecca RM, Ercole BB, Nicosia A, Tramontano A. Yagnik AT, et al. Among authors: lahm a. Proteins. 2000 Aug 15;40(3):355-66. doi: 10.1002/1097-0134(20000815)40:3<355::aid-prot20>3.0.co;2-k. Proteins. 2000. PMID: 10861927
Induction of cross-reactive humoral immune response by immunization with mimotopes of the hypervariable region 1 of the hepatitis C virus.
Roccasecca R, Folgori A, Ercole BB, Puntoriero G, Lahm A, Zucchelli S, Tafi R, Pezzanera M, Galfre G, Tramontano A, Mondelli MU, Pessi A, Nicosia A, Cortese R, Meola A. Roccasecca R, et al. Among authors: lahm a. Int Rev Immunol. 2001;20(2):289-300. doi: 10.3109/08830180109043040. Int Rev Immunol. 2001. PMID: 11878771
Binding of the hepatitis C virus E2 glycoprotein to CD81 is strain specific and is modulated by a complex interplay between hypervariable regions 1 and 2.
Roccasecca R, Ansuini H, Vitelli A, Meola A, Scarselli E, Acali S, Pezzanera M, Ercole BB, McKeating J, Yagnik A, Lahm A, Tramontano A, Cortese R, Nicosia A. Roccasecca R, et al. Among authors: lahm a. J Virol. 2003 Feb;77(3):1856-67. doi: 10.1128/jvi.77.3.1856-1867.2003. J Virol. 2003. PMID: 12525620 Free PMC article.
126 results