Giannella M - Search Results

1

Alpha2-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole.

Gentili F, Bousquet P, Brasili L, Caretto M, Carrieri A, Dontenwill M, Giannella M, Marucci G, Perfumi M, Piergentili A, Quaglia W, Rascente C, Pigini M. Gentili F, et al. Among authors: giannella m. J Med Chem. 2002 Jan 3;45(1):32-40. doi: 10.1021/jm0110082. J Med Chem. 2002. PMID: 11754577

2

Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes.

Quaglia W, Pigini M, Piergentili A, Giannella M, Gentili F, Marucci G, Carrieri A, Carotti A, Poggesi E, Leonardi A, Melchiorre C. Quaglia W, et al. Among authors: giannella m. J Med Chem. 2002 Apr 11;45(8):1633-43. doi: 10.1021/jm011066n. J Med Chem. 2002. PMID: 11931617

3

Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.

Gentili F, Bousquet P, Brasili L, Dontenwill M, Feldman J, Ghelfi F, Giannella M, Piergentili A, Quaglia W, Pigini M. Gentili F, et al. Among authors: giannella m. J Med Chem. 2003 May 22;46(11):2169-76. doi: 10.1021/jm021113r. J Med Chem. 2003. PMID: 12747788

4

Muscarinic subtypes profile modulation within a series of new antagonists, bridged bicyclic derivatives of 2,2-diphenyl-[1,3]-dioxolan-4-ylmethyl-dimethylamine.

Piergentili A, Gentili F, Ghelfi F, Marucci G, Pigini M, Quaglia W, Giannella M. Piergentili A, et al. Among authors: giannella m. Bioorg Med Chem. 2003 Sep 1;11(18):3901-11. doi: 10.1016/s0968-0896(03)00431-0. Bioorg Med Chem. 2003. PMID: 12927850

5

alpha 2-adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha 2C-subtype.

Gentili F, Ghelfi F, Giannella M, Piergentili A, Pigini M, Quaglia W, Vesprini C, Crassous PA, Paris H, Carrieri A. Gentili F, et al. Among authors: giannella m. J Med Chem. 2004 Dec 2;47(25):6160-73. doi: 10.1021/jm0408215. J Med Chem. 2004. PMID: 15566287

6

Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4-chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate cancer cell apoptosis and proliferation.

Quaglia W, Santoni G, Pigini M, Piergentili A, Gentili F, Buccioni M, Mosca M, Lucciarini R, Amantini C, Nabissi MI, Ballarini P, Poggesi E, Leonardi A, Giannella M. Quaglia W, et al. Among authors: giannella m. J Med Chem. 2005 Dec 1;48(24):7750-63. doi: 10.1021/jm0580398. J Med Chem. 2005. PMID: 16302814

7

3-[5-(4,5-dihydro-1H-imidazol-2-yl)-furan-2-yl]phenylamine (Amifuraline), a promising reversible and selective peripheral MAO-A inhibitor.

Gentili F, Pizzinat N, Ordener C, Marchal-Victorion S, Maurel A, Hofmann R, Renard P, Delagrange P, Pigini M, Parini A, Giannella M. Gentili F, et al. Among authors: giannella m. J Med Chem. 2006 Sep 7;49(18):5578-86. doi: 10.1021/jm060605r. J Med Chem. 2006. PMID: 16942031

8

Dioxane and oxathiane nuclei: suitable substructures for muscarinic agonists.

Piergentili A, Quaglia W, Giannella M, Del Bello F, Bruni B, Buccioni M, Carrieri A, Ciattini S. Piergentili A, et al. Among authors: giannella m. Bioorg Med Chem. 2007 Jan 15;15(2):886-96. doi: 10.1016/j.bmc.2006.10.040. Epub 2006 Oct 21. Bioorg Med Chem. 2007. PMID: 17084634

9

Agonists and antagonists targeting the different alpha2-adrenoceptor subtypes.

Gentili F, Pigini M, Piergentili A, Giannella M. Gentili F, et al. Among authors: giannella m. Curr Top Med Chem. 2007;7(2):163-86. doi: 10.2174/156802607779318235. Curr Top Med Chem. 2007. PMID: 17266604 Review.

10

Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist.

Crassous PA, Cardinaletti C, Carrieri A, Bruni B, Di Vaira M, Gentili F, Ghelfi F, Giannella M, Paris H, Piergentili A, Quaglia W, Schaak S, Vesprini C, Pigini M. Crassous PA, et al. Among authors: giannella m. J Med Chem. 2007 Aug 9;50(16):3964-8. doi: 10.1021/jm061487a. Epub 2007 Jul 14. J Med Chem. 2007. PMID: 17630725

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