Sporn MB - Search Results - PubMed

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510 results

Page of 51

Results are displayed in a computed author sort order. The Publication Date timeline is not available.

Page 1

1

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.

Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, Sporn MB, Andreeff M. Konopleva M, et al. Among authors: sporn mb. Blood. 2002 Jan 1;99(1):326-35. doi: 10.1182/blood.v99.1.326. Blood. 2002. PMID: 11756188 Free article.

2

2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.

Samudio I, Konopleva M, Hail N Jr, Shi YX, McQueen T, Hsu T, Evans R, Honda T, Gribble GW, Sporn M, Gilbert HF, Safe S, Andreeff M. Samudio I, et al. J Biol Chem. 2005 Oct 28;280(43):36273-82. doi: 10.1074/jbc.M507518200. Epub 2005 Aug 23. J Biol Chem. 2005. PMID: 16118208 Free article.

3

Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO).

Hail N Jr, Konopleva M, Sporn M, Lotan R, Andreeff M. Hail N Jr, et al. J Biol Chem. 2004 Mar 19;279(12):11179-87. doi: 10.1074/jbc.M312758200. Epub 2004 Jan 7. J Biol Chem. 2004. PMID: 14711815 Free article.

4

Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.

Kim KB, Lotan R, Yue P, Sporn MB, Suh N, Gribble GW, Honda T, Wu GS, Hong WK, Sun SY. Kim KB, et al. Among authors: sporn mb. Mol Cancer Ther. 2002 Jan;1(3):177-84. Mol Cancer Ther. 2002. PMID: 12467212

5

The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.

Konopleva M, Tsao T, Estrov Z, Lee RM, Wang RY, Jackson CE, McQueen T, Monaco G, Munsell M, Belmont J, Kantarjian H, Sporn MB, Andreeff M. Konopleva M, et al. Among authors: sporn mb. Cancer Res. 2004 Nov 1;64(21):7927-35. doi: 10.1158/0008-5472.CAN-03-2402. Cancer Res. 2004. PMID: 15520199

6

CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.

Koschmieder S, D'Alò F, Radomska H, Schöneich C, Chang JS, Konopleva M, Kobayashi S, Levantini E, Suh N, Di Ruscio A, Voso MT, Watt JC, Santhanam R, Sargin B, Kantarjian H, Andreeff M, Sporn MB, Perrotti D, Berdel WE, Müller-Tidow C, Serve H, Tenen DG. Koschmieder S, et al. Among authors: sporn mb. Blood. 2007 Nov 15;110(10):3695-705. doi: 10.1182/blood-2006-11-058941. Epub 2007 Aug 1. Blood. 2007. PMID: 17671235 Free PMC article. Clinical Trial.

7

The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance.

Ikeda T, Sporn M, Honda T, Gribble GW, Kufe D. Ikeda T, et al. Cancer Res. 2003 Sep 1;63(17):5551-8. Cancer Res. 2003. PMID: 14500394

8

The triterpenoid CDDO induces apoptosis in refractory CLL B cells.

Pedersen IM, Kitada S, Schimmer A, Kim Y, Zapata JM, Charboneau L, Rassenti L, Andreeff M, Bennett F, Sporn MB, Liotta LD, Kipps TJ, Reed JC. Pedersen IM, et al. Among authors: sporn mb. Blood. 2002 Oct 15;100(8):2965-72. doi: 10.1182/blood-2002-04-1174. Blood. 2002. PMID: 12351409 Free article.

9

Retraction: The triterpenoid CDDO-Imidazolide induces apoptosis and enhances fludarabine-induced apoptosis of CLL B-cells.

Pedersen IM, Zapata JM, Samuel T, Scott FL, Salvesen GS, Honda T, Gribble GW, Suh N, Sporn MB, Kipps TJ, Reed JC. Pedersen IM, et al. Among authors: sporn mb. Blood. 2004 Aug 15;104(4):932. doi: 10.1182/blood-2003-11-3774. Epub 2004 Jan 22. Blood. 2004. PMID: 14739219 Free article. Retracted. No abstract available.

10

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.

Chauhan D, Li G, Podar K, Hideshima T, Shringarpure R, Catley L, Mitsiades C, Munshi N, Tai YT, Suh N, Gribble GW, Honda T, Schlossman R, Richardson P, Sporn MB, Anderson KC. Chauhan D, et al. Among authors: sporn mb. Blood. 2004 Apr 15;103(8):3158-66. doi: 10.1182/blood-2003-08-2873. Epub 2003 Dec 11. Blood. 2004. PMID: 15070698 Free article.

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