Jonas JC - Search Results

1

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia.

Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Laybutt DR, et al. Among authors: jonas jc. Diabetes. 2002 Feb;51(2):413-23. doi: 10.2337/diabetes.51.2.413. Diabetes. 2002. PMID: 11812749

2

Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.

Pertusa JA, Nesher R, Kaiser N, Cerasi E, Henquin JC, Jonas JC. Pertusa JA, et al. Among authors: jonas jc. Diabetes. 2002 Aug;51(8):2552-60. doi: 10.2337/diabetes.51.8.2552. Diabetes. 2002. PMID: 12145170

3

Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.

Bensellam M, Duvillié B, Rybachuk G, Laybutt DR, Magnan C, Guiot Y, Pouysségur J, Jonas JC. Bensellam M, et al. Among authors: jonas jc. PLoS One. 2012;7(1):e29807. doi: 10.1371/journal.pone.0029807. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235342 Free PMC article.

4

The molecular mechanisms of pancreatic β-cell glucotoxicity: recent findings and future research directions.

Bensellam M, Laybutt DR, Jonas JC. Bensellam M, et al. Among authors: jonas jc. Mol Cell Endocrinol. 2012 Nov 25;364(1-2):1-27. doi: 10.1016/j.mce.2012.08.003. Epub 2012 Aug 10. Mol Cell Endocrinol. 2012. PMID: 22885162 Review.

5

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

Bensellam M, Maxwell EL, Chan JY, Luzuriaga J, West PK, Jonas JC, Gunton JE, Laybutt DR. Bensellam M, et al. Among authors: jonas jc. Diabetologia. 2016 Jul;59(7):1492-1502. doi: 10.1007/s00125-016-3947-y. Epub 2016 Apr 4. Diabetologia. 2016. PMID: 27039902

6

Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions.

Bensellam M, Jonas JC, Laybutt DR. Bensellam M, et al. Among authors: jonas jc. J Endocrinol. 2018 Feb;236(2):R109-R143. doi: 10.1530/JOE-17-0516. Epub 2017 Dec 4. J Endocrinol. 2018. PMID: 29203573 Review.

7

Phlda3 regulates beta cell survival during stress.

Bensellam M, Chan JY, Lee K, Joglekar MV, Hardikar AA, Loudovaris T, Thomas HE, Jonas JC, Laybutt DR. Bensellam M, et al. Among authors: jonas jc. Sci Rep. 2019 Sep 6;9(1):12827. doi: 10.1038/s41598-019-49289-5. Sci Rep. 2019. PMID: 31492921 Free PMC article.

8

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.

Bensellam M, Shi YC, Chan JY, Laybutt DR, Chae H, Abou-Samra M, Pappas EG, Thomas HE, Gilon P, Jonas JC. Bensellam M, et al. Among authors: jonas jc. Diabetologia. 2019 Dec;62(12):2273-2286. doi: 10.1007/s00125-019-05008-3. Epub 2019 Oct 17. Diabetologia. 2019. PMID: 31624901

9

Emerging Roles of Metallothioneins in Beta Cell Pathophysiology: Beyond and Above Metal Homeostasis and Antioxidant Response.

Bensellam M, Laybutt DR, Jonas JC. Bensellam M, et al. Among authors: jonas jc. Biology (Basel). 2021 Feb 26;10(3):176. doi: 10.3390/biology10030176. Biology (Basel). 2021. PMID: 33652748 Free PMC article. Review.

10

Transcriptome analysis of islets from diabetes-resistant and diabetes-prone obese mice reveals novel gene regulatory networks involved in beta-cell compensation and failure.

Chan JY, Bensellam M, Lin RCY, Liang C, Lee K, Jonas JC, Laybutt DR. Chan JY, et al. Among authors: jonas jc. FASEB J. 2021 Jun;35(6):e21608. doi: 10.1096/fj.202100009R. FASEB J. 2021. PMID: 33977593

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