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Th1 and Th2 cells help CD8 T-cell responses.
Ekkens MJ, Shedlock DJ, Jung E, Troy A, Pearce EL, Shen H, Pearce EJ. Ekkens MJ, et al. Among authors: shedlock dj. Infect Immun. 2007 May;75(5):2291-6. doi: 10.1128/IAI.01328-06. Epub 2007 Feb 26. Infect Immun. 2007. PMID: 17325050 Free PMC article.
HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells.
Muthumani K, Shedlock DJ, Choo DK, Fagone P, Kawalekar OU, Goodman J, Bian CB, Ramanathan AA, Atman P, Tebas P, Chattergoon MA, Choo AY, Weiner DB. Muthumani K, et al. Among authors: shedlock dj. J Immunol. 2011 Sep 15;187(6):2932-43. doi: 10.4049/jimmunol.1100594. Epub 2011 Aug 19. J Immunol. 2011. PMID: 21856939 Free PMC article.
A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge.
Shedlock DJ, Talbott KT, Cress C, Ferraro B, Tuyishme S, Mallilankaraman K, Cisper NJ, Morrow MP, Wu SJ, Kawalekar OU, Khan AS, Sardesai NY, Muthumani K, Shen H, Weiner DB. Shedlock DJ, et al. Vaccine. 2011 Sep 9;29(39):6755-62. doi: 10.1016/j.vaccine.2010.12.064. Epub 2011 Jan 14. Vaccine. 2011. PMID: 21238574 Free PMC article.
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