Groves P - Search Results

1

A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression.

Kienzle N, Buttigieg K, Groves P, Kawula T, Kelso A. Kienzle N, et al. Among authors: groves p. J Immunol. 2002 Feb 15;168(4):1672-81. doi: 10.4049/jimmunol.168.4.1672. J Immunol. 2002. PMID: 11823496

2

Rapid establishment of a stable IL-4/IFN-gamma production profile in the antigen-specific CD4+ T cell response to protein immunization.

Kelso A, Groves P, Troutt AB, Pech MH. Kelso A, et al. Among authors: groves p. Int Immunol. 1994 Oct;6(10):1515-23. doi: 10.1093/intimm/6.10.1515. Int Immunol. 1994. PMID: 7530038

3

Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like response in vivo.

Kelso A, Groves P, Troutt AB, Francis K. Kelso A, et al. Among authors: groves p. Eur J Immunol. 1995 May;25(5):1168-75. doi: 10.1002/eji.1830250506. Eur J Immunol. 1995. PMID: 7774620

4

Limiting dilution analysis reveals the precursors of interleukin-4-producing CD4+ cells induced by protein immunization.

Groves PL, Pech MH, Troutt AB, Kelso A. Groves PL, et al. Immunology. 1994 Sep;83(1):25-32. Immunology. 1994. PMID: 7821962 Free PMC article.

5

A single peripheral CD8+ T cell can give rise to progeny expressing type 1 and/or type 2 cytokine genes and can retain its multipotentiality through many cell divisions.

Kelso A, Groves P. Kelso A, et al. Among authors: groves p. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8070-5. doi: 10.1073/pnas.94.15.8070. Proc Natl Acad Sci U S A. 1997. PMID: 9223316 Free PMC article.

6

Single-cell analysis by RT-PCR reveals differential expression of multiple type 1 and 2 cytokine genes among cells within polarized CD4+ T cell populations.

Kelso A, Groves P, Ramm L, Doyle AG. Kelso A, et al. Among authors: groves p. Int Immunol. 1999 Apr;11(4):617-21. doi: 10.1093/intimm/11.4.617. Int Immunol. 1999. PMID: 10323215

7

The activated type 1-polarized CD8(+) T cell population isolated from an effector site contains cells with flexible cytokine profiles.

Doyle AG, Buttigieg K, Groves P, Johnson BJ, Kelso A. Doyle AG, et al. Among authors: groves p. J Exp Med. 1999 Oct 18;190(8):1081-92. doi: 10.1084/jem.190.8.1081. J Exp Med. 1999. PMID: 10523606 Free PMC article.

8

The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8(+) T cells during primary activation.

Kelso A, Costelloe EO, Johnson BJ, Groves P, Buttigieg K, Fitzpatrick DR. Kelso A, et al. Among authors: groves p. Int Immunol. 2002 Jun;14(6):605-13. doi: 10.1093/intimm/dxf028. Int Immunol. 2002. PMID: 12039912

9

Progressive differentiation and commitment of CD8+ T cells to a poorly cytolytic CD8low phenotype in the presence of IL-4.

Kienzle N, Olver S, Buttigieg K, Groves P, Janas ML, Baz A, Kelso A. Kienzle N, et al. Among authors: groves p. J Immunol. 2005 Feb 15;174(4):2021-9. doi: 10.4049/jimmunol.174.4.2021. J Immunol. 2005. PMID: 15699131

10

IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation.

Janas ML, Groves P, Kienzle N, Kelso A. Janas ML, et al. Among authors: groves p. J Immunol. 2005 Dec 15;175(12):8003-10. doi: 10.4049/jimmunol.175.12.8003. J Immunol. 2005. PMID: 16339537

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