Clapham JC - Search Results

1

Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice.

Haynes AC, Chapman H, Taylor C, Moore GB, Cawthorne MA, Tadayyon M, Clapham JC, Arch JR. Haynes AC, et al. Among authors: clapham jc. Regul Pept. 2002 Mar 15;104(1-3):153-9. doi: 10.1016/s0167-0115(01)00358-5. Regul Pept. 2002. PMID: 11830290

2

Anti-obesity drugs: a critical review of current therapies and future opportunities.

Clapham JC, Arch JR, Tadayyon M. Clapham JC, et al. Pharmacol Ther. 2001 Jan;89(1):81-121. doi: 10.1016/s0163-7258(00)00105-4. Pharmacol Ther. 2001. PMID: 11316515 Review.

3

Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter.

Pearce NJ, Arch JR, Clapham JC, Coghlan MP, Corcoran SL, Lister CA, Llano A, Moore GB, Murphy GJ, Smith SA, Taylor CM, Yates JW, Morrison AD, Harper AJ, Roxbee-Cox L, Abuin A, Wargent E, Holder JC. Pearce NJ, et al. Among authors: clapham jc. Metabolism. 2004 Oct;53(10):1322-30. doi: 10.1016/j.metabol.2004.05.008. Metabolism. 2004. PMID: 15375789

4

Targeting thermogenesis and related pathways in anti-obesity drug discovery.

Clapham JC, Arch JR. Clapham JC, et al. Pharmacol Ther. 2011 Sep;131(3):295-308. doi: 10.1016/j.pharmthera.2011.04.004. Epub 2011 Apr 13. Pharmacol Ther. 2011. PMID: 21514319 Review.

5

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean.

Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, Piercy V, Carter SA, Lehner I, Smith SA, Beeley LJ, Godden RJ, Herrity N, Skehel M, Changani KK, Hockings PD, Reid DG, Squires SM, Hatcher J, Trail B, Latcham J, Rastan S, Harper AJ, Cadenas S, Buckingham JA, Brand MD, Abuin A. Clapham JC, et al. Nature. 2000 Jul 27;406(6794):415-8. doi: 10.1038/35019082. Nature. 2000. PMID: 10935638

6

Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice.

Moore GB, Chapman H, Holder JC, Lister CA, Piercy V, Smith SA, Clapham JC. Moore GB, et al. Among authors: clapham jc. Biochem Biophys Res Commun. 2001 Aug 31;286(4):735-41. doi: 10.1006/bbrc.2001.5460. Biochem Biophys Res Commun. 2001. PMID: 11520059

7

Concordant mRNA expression of UCP-3, but not UCP-2, with mitochondrial thioesterase-1 in brown adipose tissue and skeletal muscle in db/db diabetic mice.

Clapham JC, Coulthard VH, Moore GB. Clapham JC, et al. Biochem Biophys Res Commun. 2001 Oct 12;287(5):1058-62. doi: 10.1006/bbrc.2001.5698. Biochem Biophys Res Commun. 2001. PMID: 11587528

8

Enhanced diabetogenic effect of streptozotocin in mice overexpressing UCP-3 in skeletal muscle.

Wang S, Cawthorne MA, Clapham JC. Wang S, et al. Among authors: clapham jc. Ann N Y Acad Sci. 2002 Jun;967:112-9. doi: 10.1111/j.1749-6632.2002.tb04269.x. Ann N Y Acad Sci. 2002. PMID: 12079841

9

Orexins and feeding: special occasions or everyday occurrence?

Cai XJ, Liu XH, Evans M, Clapham JC, Wilson S, Arch JR, Morris R, Williams G. Cai XJ, et al. Among authors: clapham jc. Regul Pept. 2002 Mar 15;104(1-3):1-9. doi: 10.1016/s0167-0115(01)00343-3. Regul Pept. 2002. PMID: 11830270 Review.

10

Hypothalamic orexin expression: modulation by blood glucose and feeding.

Cai XJ, Widdowson PS, Harrold J, Wilson S, Buckingham RE, Arch JR, Tadayyon M, Clapham JC, Wilding J, Williams G. Cai XJ, et al. Among authors: clapham jc. Diabetes. 1999 Nov;48(11):2132-7. doi: 10.2337/diabetes.48.11.2132. Diabetes. 1999. PMID: 10535445

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