Diehl TS - Search Results

1

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.

Esler WP, Kimberly WT, Ostaszewski BL, Ye W, Diehl TS, Selkoe DJ, Wolfe MS. Esler WP, et al. Among authors: diehl ts. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2720-5. doi: 10.1073/pnas.052436599. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867728 Free PMC article.

2

Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).

Kimberly WT, Esler WP, Ye W, Ostaszewski BL, Gao J, Diehl T, Selkoe DJ, Wolfe MS. Kimberly WT, et al. Biochemistry. 2003 Jan 14;42(1):137-44. doi: 10.1021/bi026888g. Biochemistry. 2003. PMID: 12515548

3

Active gamma-secretase complexes contain only one of each component.

Sato T, Diehl TS, Narayanan S, Funamoto S, Ihara Y, De Strooper B, Steiner H, Haass C, Wolfe MS. Sato T, et al. Among authors: diehl ts. J Biol Chem. 2007 Nov 23;282(47):33985-93. doi: 10.1074/jbc.M705248200. Epub 2007 Oct 2. J Biol Chem. 2007. PMID: 17911105 Free article.

4

Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities.

Citron M, Diehl TS, Gordon G, Biere AL, Seubert P, Selkoe DJ. Citron M, et al. Among authors: diehl ts. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13170-5. doi: 10.1073/pnas.93.23.13170. Proc Natl Acad Sci U S A. 1996. PMID: 8917563 Free PMC article.

5

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ. Wolfe MS, et al. Among authors: diehl ts. Nature. 1999 Apr 8;398(6727):513-7. doi: 10.1038/19077. Nature. 1999. PMID: 10206644

6

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

Esler WP, Kimberly WT, Ostaszewski BL, Diehl TS, Moore CL, Tsai JY, Rahmati T, Xia W, Selkoe DJ, Wolfe MS. Esler WP, et al. Among authors: diehl ts. Nat Cell Biol. 2000 Jul;2(7):428-34. doi: 10.1038/35017062. Nat Cell Biol. 2000. PMID: 10878808

7

Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase.

Esler WP, Das C, Campbell WA, Kimberly WT, Kornilova AY, Diehl TS, Ye W, Ostaszewski BL, Xia W, Selkoe DJ, Wolfe MS. Esler WP, et al. Among authors: diehl ts. Nat Cell Biol. 2002 May;4(5):E110-1; author reply E111-2. doi: 10.1038/ncb0502-e110b. Nat Cell Biol. 2002. PMID: 11988746 No abstract available.

8

Designed helical peptides inhibit an intramembrane protease.

Das C, Berezovska O, Diehl TS, Genet C, Buldyrev I, Tsai JY, Hyman BT, Wolfe MS. Das C, et al. Among authors: diehl ts. J Am Chem Soc. 2003 Oct 1;125(39):11794-5. doi: 10.1021/ja037131v. J Am Chem Soc. 2003. PMID: 14505382

9

Signal peptide peptidase: biochemical properties and modulation by nonsteroidal antiinflammatory drugs.

Sato T, Nyborg AC, Iwata N, Diehl TS, Saido TC, Golde TE, Wolfe MS. Sato T, et al. Among authors: diehl ts. Biochemistry. 2006 Jul 18;45(28):8649-56. doi: 10.1021/bi060597g. Biochemistry. 2006. PMID: 16834339

10

A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity.

Wolfe MS, Citron M, Diehl TS, Xia W, Donkor IO, Selkoe DJ. Wolfe MS, et al. Among authors: diehl ts. J Med Chem. 1998 Jan 1;41(1):6-9. doi: 10.1021/jm970621b. J Med Chem. 1998. PMID: 9438016 No abstract available.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

20 results

Search Page

Filters