Selkoe DJ - Search Results

1

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate.

Esler WP, Kimberly WT, Ostaszewski BL, Ye W, Diehl TS, Selkoe DJ, Wolfe MS. Esler WP, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2720-5. doi: 10.1073/pnas.052436599. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867728 Free PMC article.

2

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage.

Hung AY, Koo EH, Haass C, Selkoe DJ. Hung AY, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9439-43. doi: 10.1073/pnas.89.20.9439. Proc Natl Acad Sci U S A. 1992. PMID: 1409654 Free PMC article.

3

Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels.

Tamaoka A, Kalaria RN, Lieberburg I, Selkoe DJ. Tamaoka A, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 1992 Feb 15;89(4):1345-9. doi: 10.1073/pnas.89.4.1345. Proc Natl Acad Sci U S A. 1992. PMID: 1531538 Free PMC article.

4

Detection of distinct isoform patterns of the beta-amyloid precursor protein in human platelets and lymphocytes.

Schlossmacher MG, Ostaszewski BL, Hecker LI, Celi A, Haass C, Chin D, Lieberburg I, Furie BC, Furie B, Selkoe DJ. Schlossmacher MG, et al. Among authors: selkoe dj. Neurobiol Aging. 1992 May-Jun;13(3):421-34. doi: 10.1016/0197-4580(92)90117-g. Neurobiol Aging. 1992. PMID: 1625772

5

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

Selkoe DJ, Podlisny MB, Joachim CL, Vickers EA, Lee G, Fritz LC, Oltersdorf T. Selkoe DJ, et al. Proc Natl Acad Sci U S A. 1988 Oct;85(19):7341-5. doi: 10.1073/pnas.85.19.7341. Proc Natl Acad Sci U S A. 1988. PMID: 3140239 Free PMC article.

6

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.

Kirschner DA, Inouye H, Duffy LK, Sinclair A, Lind M, Selkoe DJ. Kirschner DA, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 1987 Oct;84(19):6953-7. doi: 10.1073/pnas.84.19.6953. Proc Natl Acad Sci U S A. 1987. PMID: 3477820 Free PMC article.

7

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway.

Haass C, Lemere CA, Capell A, Citron M, Seubert P, Schenk D, Lannfelt L, Selkoe DJ. Haass C, et al. Among authors: selkoe dj. Nat Med. 1995 Dec;1(12):1291-6. doi: 10.1038/nm1295-1291. Nat Med. 1995. PMID: 7489411

8

Generation of amyloid beta protein from its precursor is sequence specific.

Citron M, Teplow DB, Selkoe DJ. Citron M, et al. Among authors: selkoe dj. Neuron. 1995 Mar;14(3):661-70. doi: 10.1016/0896-6273(95)90323-2. Neuron. 1995. PMID: 7695913 Free article.

9

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.

Podlisny MB, Ostaszewski BL, Squazzo SL, Koo EH, Rydell RE, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: selkoe dj. J Biol Chem. 1995 Apr 21;270(16):9564-70. doi: 10.1074/jbc.270.16.9564. J Biol Chem. 1995. PMID: 7721886 Free article.

10

Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation.

Citron M, Vigo-Pelfrey C, Teplow DB, Miller C, Schenk D, Johnston J, Winblad B, Venizelos N, Lannfelt L, Selkoe DJ. Citron M, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11993-7. doi: 10.1073/pnas.91.25.11993. Proc Natl Acad Sci U S A. 1994. PMID: 7991571 Free PMC article.

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