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554 results

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Page 1
Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton.
Connolly S, Bennion C, Botterell S, Croshaw PJ, Hallam C, Hardy K, Hartopp P, Jackson CG, King SJ, Lawrence L, Mete A, Murray D, Robinson DH, Smith GM, Stein L, Walters I, Wells E, Withnall WJ. Connolly S, et al. Among authors: wells e. J Med Chem. 2002 Mar 14;45(6):1348-62. doi: 10.1021/jm011050x. J Med Chem. 2002. PMID: 11882004
Synthesis and evaluation of substrate-mimicking cytosolic phospholipase A2 inhibitors--reducing the lipophilicity of the arachidonyl chain isostere.
Walters I, Bennion C, Connolly S, Croshaw PJ, Hardy K, Hartopp P, Jackson CG, King SJ, Lawrence L, Mete A, Murray D, Robinson DH, Stein L, Wells E, John Withnall W. Walters I, et al. Among authors: wells e. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3645-9. doi: 10.1016/j.bmcl.2004.05.024. Bioorg Med Chem Lett. 2004. PMID: 15203135
The discovery of MMP7 inhibitors exploiting a novel selectivity trigger.
Edman K, Furber M, Hemsley P, Johansson C, Pairaudeau G, Petersen J, Stocks M, Tervo A, Ward A, Wells E, Wissler L. Edman K, et al. Among authors: wells e. ChemMedChem. 2011 May 2;6(5):769-73. doi: 10.1002/cmdc.201000550. Epub 2011 Feb 18. ChemMedChem. 2011. PMID: 21520417 No abstract available.
Development of a homogeneous high-throughput screening assay for biological inhibitors of human rhinovirus infection.
Newton P, O'Shea D, Wells E, Moakes K, Dunmore R, Butler RJ, Wilkinson T, Ward A, Casson N, Strain M, Vousden K, Lowe DC, Pattison DV, Carruthers AM, Sleeman MA, Vaughan TJ, Harrison P. Newton P, et al. Among authors: wells e. J Biomol Screen. 2013 Mar;18(3):237-46. doi: 10.1177/1087057112469047. Epub 2012 Dec 3. J Biomol Screen. 2013. PMID: 23207740
Valproate-Induced Thrombocytopenia: A Case Report.
Surineni K, Wells E, Schrader N, Costa G, Ziegler M. Surineni K, et al. Among authors: wells e. Cureus. 2024 Jul 29;16(7):e65670. doi: 10.7759/cureus.65670. eCollection 2024 Jul. Cureus. 2024. PMID: 39205734 Free PMC article.
554 results