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In vitro and in vivo activities of a novel cephalosporin, BMS-247243, against methicillin-resistant and -susceptible staphylococci.
Fung-Tomc JC, Clark J, Minassian B, Pucci M, Tsai YH, Gradelski E, Lamb L, Medina I, Huczko E, Kolek B, Chaniewski S, Ferraro C, Washo T, Bonner DP. Fung-Tomc JC, et al. Among authors: medina i. Antimicrob Agents Chemother. 2002 Apr;46(4):971-6. doi: 10.1128/AAC.46.4.971-976.2002. Antimicrob Agents Chemother. 2002. PMID: 11897577 Free PMC article.
Orally active fusion inhibitor of respiratory syncytial virus.
Cianci C, Yu KL, Combrink K, Sin N, Pearce B, Wang A, Civiello R, Voss S, Luo G, Kadow K, Genovesi EV, Venables B, Gulgeze H, Trehan A, James J, Lamb L, Medina I, Roach J, Yang Z, Zadjura L, Colonno R, Clark J, Meanwell N, Krystal M. Cianci C, et al. Among authors: medina i. Antimicrob Agents Chemother. 2004 Feb;48(2):413-22. doi: 10.1128/AAC.48.2.413-422.2004. Antimicrob Agents Chemother. 2004. PMID: 14742189 Free PMC article.
Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection.
Cianci C, Genovesi EV, Lamb L, Medina I, Yang Z, Zadjura L, Yang H, D'Arienzo C, Sin N, Yu KL, Combrink K, Li Z, Colonno R, Meanwell N, Clark J, Krystal M. Cianci C, et al. Among authors: medina i. Antimicrob Agents Chemother. 2004 Jul;48(7):2448-54. doi: 10.1128/AAC.48.7.2448-2454.2004. Antimicrob Agents Chemother. 2004. PMID: 15215093 Free PMC article.
Venables, H. Gulgeze, A. Trehan, J. James, L. Lamb, I. Medina, J. Roach, Z. Yang, L. Zadjura, R. Colonno, J. Clark, N. Meanwell, and M. ...A single oral dose, administered 1 h prior to intranasal RSV inoculation, was as effective against infection as a 4-day b.i …
Venables, H. Gulgeze, A. Trehan, J. James, L. Lamb, I. Medina, J. Roach, Z. Yang, L. Zadjura, R. Colonno, J. Clark, N. Meanwel …
Effect of linezolid on the 50% lethal dose and 50% protective dose in treatment of infections by Gram-negative pathogens in naive and immunosuppressed mice and on the efficacy of ciprofloxacin in an acute murine model of septicemia.
Marra A, Lamb L, Medina I, George D, Gibson G, Hardink J, Rugg J, Van Deusen J, O'Donnell JP. Marra A, et al. Among authors: medina i. Antimicrob Agents Chemother. 2012 Sep;56(9):4671-5. doi: 10.1128/AAC.00276-12. Epub 2012 Jun 18. Antimicrob Agents Chemother. 2012. PMID: 22710118 Free PMC article.
Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo.
Yu KL, Wang XA, Civiello RL, Trehan AK, Pearce BC, Yin Z, Combrink KD, Gulgeze HB, Zhang Y, Kadow KF, Cianci CW, Clarke J, Genovesi EV, Medina I, Lamb L, Wyde PR, Krystal M, Meanwell NA. Yu KL, et al. Among authors: medina i. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1115-22. doi: 10.1016/j.bmcl.2005.11.109. Epub 2005 Dec 20. Bioorg Med Chem Lett. 2006. PMID: 16368233
350 results