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Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses.
Urano W, Taniguchi A, Yamanaka H, Tanaka E, Nakajima H, Matsuda Y, Akama H, Kitamura Y, Kamatani N. Urano W, et al. Pharmacogenetics. 2002 Apr;12(3):183-90. doi: 10.1097/00008571-200204000-00002. Pharmacogenetics. 2002. PMID: 11927833
Pharmacogenetics of disease-modifying anti-rheumatic drugs.
Tanaka E, Taniguchi A, Urano W, Yamanaka H, Kamatani N. Tanaka E, et al. Among authors: urano w. Best Pract Res Clin Rheumatol. 2004 Apr;18(2):233-47. doi: 10.1016/j.berh.2004.02.006. Best Pract Res Clin Rheumatol. 2004. PMID: 15121042 Review.
[Pharmacogenomics of the immunosuppressive agents].
Taniguchi A, Urano W, Tanaka E, Kitamura Y, Saito M, Akama H, Yamanak H, Saito T, Kamatani N. Taniguchi A, et al. Among authors: urano w. Nihon Rinsho Meneki Gakkai Kaishi. 2002 Feb;25(1):105-9. Nihon Rinsho Meneki Gakkai Kaishi. 2002. PMID: 11963167 Review. Japanese. No abstract available.
Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice.
Taniguchi A, Urano W, Tanaka E, Furihata S, Kamitsuji S, Inoue E, Yamanaka M, Yamanaka H, Kamatani N. Taniguchi A, et al. Among authors: urano w. Pharmacogenet Genomics. 2007 Jun;17(6):383-90. doi: 10.1097/01.fpc.0000236326.80809.b1. Pharmacogenet Genomics. 2007. PMID: 17502830
Associations between methotrexate treatment and methylenetetrahydrofolate reductase gene polymorphisms with incident fractures in Japanese female rheumatoid arthritis patients.
Urano W, Furuya T, Inoue E, Taniguchi A, Urano T, Kotake S, Sekita C, Inoue S, Hara M, Momohara S, Kamatani N, Yamanaka H. Urano W, et al. Among authors: urano t. J Bone Miner Metab. 2009;27(5):574-83. doi: 10.1007/s00774-009-0073-7. Epub 2009 Mar 31. J Bone Miner Metab. 2009. PMID: 19333678
25 results