Bovenschen N - Search Results

1

Two classes of germline genes both derived from the V(H)1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII.

van den Brink EN, Bril WS, Turenhout EA, Zuurveld M, Bovenschen N, Peters M, Yee TT, Mertens K, Lewis DA, Ortel TL, Lollar P, Scandella D, Voorberg J. van den Brink EN, et al. Among authors: bovenschen n. Blood. 2002 Apr 15;99(8):2828-34. doi: 10.1182/blood.v99.8.2828. Blood. 2002. PMID: 11929772 Free article.

2

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

Bovenschen N, Mertens K, Hu L, Havekes LM, van Vlijmen BJ. Bovenschen N, et al. Blood. 2005 Aug 1;106(3):906-12. doi: 10.1182/blood-2004-11-4230. Epub 2005 Apr 19. Blood. 2005. PMID: 15840700 Free article.

3

Human antibodies with specificity for the C2 domain of factor VIII are derived from VH1 germline genes.

van Den Brink EN, Turenhout EA, Davies J, Bovenschen N, Fijnvandraat K, Ouwehand WH, Peters M, Voorberg J. van Den Brink EN, et al. Among authors: bovenschen n. Blood. 2000 Jan 15;95(2):558-63. Blood. 2000. PMID: 10627462 Free article.

4

Multiple VH genes are used to assemble human antibodies directed toward the A3-C1 domains of factor VIII.

van den Brink EN, Turenhout EA, Bovenschen N, Heijnen BG, Mertens K, Peters M, Voorberg J. van den Brink EN, et al. Among authors: bovenschen n. Blood. 2001 Feb 15;97(4):966-72. doi: 10.1182/blood.v97.4.966. Blood. 2001. PMID: 11159524 Free article.

5

Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency.

Bovenschen N, Herz J, Grimbergen JM, Lenting PJ, Havekes LM, Mertens K, van Vlijmen BJ. Bovenschen N, et al. Blood. 2003 May 15;101(10):3933-9. doi: 10.1182/blood-2002-07-2081. Epub 2003 Jan 9. Blood. 2003. PMID: 12522008 Free article.

6

Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

Bovenschen N, Boertjes RC, van Stempvoort G, Voorberg J, Lenting PJ, Meijer AB, Mertens K. Bovenschen N, et al. J Biol Chem. 2003 Mar 14;278(11):9370-7. doi: 10.1074/jbc.M212053200. Epub 2003 Jan 8. J Biol Chem. 2003. PMID: 12522143 Free article.

7

Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.

Lewis DA, Bovenschen N, Mertens K, Voorberg J, Ortel TL. Lewis DA, et al. Among authors: bovenschen n. Thromb Haemost. 2005 May;93(5):833-41. doi: 10.1160/TH04-11-0729. Thromb Haemost. 2005. PMID: 15886796

8

The B domain of coagulation factor VIII interacts with the asialoglycoprotein receptor.

Bovenschen N, Rijken DC, Havekes LM, van Vlijmen BJ, Mertens K. Bovenschen N, et al. J Thromb Haemost. 2005 Jun;3(6):1257-65. doi: 10.1111/j.1538-7836.2005.01389.x. J Thromb Haemost. 2005. PMID: 15946216 Free article.

9

Proteolytic cleavage of factor VIII heavy chain is required to expose the binding-site for low-density lipoprotein receptor-related protein within the A2 domain.

Bovenschen N, van Stempvoort G, Voorberg J, Mertens K, Meijer AB. Bovenschen N, et al. J Thromb Haemost. 2006 Jul;4(7):1487-93. doi: 10.1111/j.1538-7836.2006.01965.x. J Thromb Haemost. 2006. PMID: 16839343 Free article.

10

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

Bovenschen N, van Dijk KW, Havekes LM, Mertens K, van Vlijmen BJ. Bovenschen N, et al. Br J Haematol. 2004 Sep;126(5):722-5. doi: 10.1111/j.1365-2141.2004.05093.x. Br J Haematol. 2004. PMID: 15327526 Free article.

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