Lamb DC - Search Results

1

The cytochrome P450 complement (CYPome) of Streptomyces coelicolor A3(2).

Lamb DC, Skaug T, Song HL, Jackson CJ, Podust LM, Waterman MR, Kell DB, Kelly DE, Kelly SL. Lamb DC, et al. J Biol Chem. 2002 Jul 5;277(27):24000-5. doi: 10.1074/jbc.M111109200. Epub 2002 Apr 9. J Biol Chem. 2002. PMID: 11943767 Free article.

2

Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol.

Kelly SL, Lamb DC, Corran AJ, Baldwin BC, Kelly DE. Kelly SL, et al. Among authors: lamb dc. Biochem Biophys Res Commun. 1995 Feb 27;207(3):910-5. doi: 10.1006/bbrc.1995.1272. Biochem Biophys Res Commun. 1995. PMID: 7864896

3

Benzo(a)pyrene hydroxylase activity in yeast is mediated by P450 other than sterol 14 alpha-demethylase.

Kelly SL, Lamb DC, Baldwin BC, Kelly DE. Kelly SL, et al. Among authors: lamb dc. Biochem Biophys Res Commun. 1993 Dec 15;197(2):428-32. doi: 10.1006/bbrc.1993.2497. Biochem Biophys Res Commun. 1993. PMID: 8267577

4

Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol delta 22-desaturase.

Kelly SL, Lamb DC, Corran AJ, Baldwin BC, Parks LW, Kelly DE. Kelly SL, et al. Among authors: lamb dc. FEBS Lett. 1995 Dec 18;377(2):217-20. doi: 10.1016/0014-5793(95)01342-3. FEBS Lett. 1995. PMID: 8543054 Free article.

5

The mechanism of the acyl-carbon bond cleavage reaction catalyzed by recombinant sterol 14 alpha-demethylase of Candida albicans (other names are: lanosterol 14 alpha-demethylase, P-45014DM, and CYP51).

Shyadehi AZ, Lamb DC, Kelly SL, Kelly DE, Schunck WH, Wright JN, Corina D, Akhtar M. Shyadehi AZ, et al. Among authors: lamb dc. J Biol Chem. 1996 May 24;271(21):12445-50. doi: 10.1074/jbc.271.21.12445. J Biol Chem. 1996. PMID: 8647850 Free article.

6

Resistance to fluconazole and amphotericin in Candida albicans from AIDS patients.

Kelly SL, Lamb DC, Kelly DE, Loeffler J, Einsele H. Kelly SL, et al. Among authors: lamb dc. Lancet. 1996 Nov 30;348(9040):1523-4. doi: 10.1016/S0140-6736(05)65949-1. Lancet. 1996. PMID: 8942815 No abstract available.

7

The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity.

Lamb DC, Kelly DE, Schunck WH, Shyadehi AZ, Akhtar M, Lowe DJ, Baldwin BC, Kelly SL. Lamb DC, et al. J Biol Chem. 1997 Feb 28;272(9):5682-8. doi: 10.1074/jbc.272.9.5682. J Biol Chem. 1997. PMID: 9038178 Free article.

8

Characterization of Saccharomyces cerevisiae CYP61, sterol delta22-desaturase, and inhibition by azole antifungal agents.

Kelly SL, Lamb DC, Baldwin BC, Corran AJ, Kelly DE. Kelly SL, et al. Among authors: lamb dc. J Biol Chem. 1997 Apr 11;272(15):9986-8. doi: 10.1074/jbc.272.15.9986. J Biol Chem. 1997. PMID: 9092539 Free article.

9

Differential inhibition of Candida albicans CYP51 with azole antifungal stereoisomers.

Lamb DC, Kelly DE, Baldwin BC, Gozzo F, Boscott P, Richards WG, Kelly SL. Lamb DC, et al. FEMS Microbiol Lett. 1997 Apr 1;149(1):25-30. doi: 10.1111/j.1574-6968.1997.tb10303.x. FEMS Microbiol Lett. 1997. PMID: 9103974

10

Reduced intracellular accumulation of azole antifungal results in resistance in Candida albicans isolate NCPF 3363.

Lamb DC, Kelly DE, Manning NJ, Kelly SL. Lamb DC, et al. FEMS Microbiol Lett. 1997 Feb 15;147(2):189-93. doi: 10.1111/j.1574-6968.1997.tb10240.x. FEMS Microbiol Lett. 1997. PMID: 9119192

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