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Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA. Zuegg J, et al. Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719. Nat Commun. 2015. PMID: 26194781 Free PMC article.
A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.
Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W. Thanh GL, et al. J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919. J Org Chem. 2010. PMID: 19961235