Worthen DR - Search Results

1

The antiproliferative and immunotoxic effects of L-canavanine and L-canaline.

Bence AK, Worthen DR, Adams VR, Crooks PA. Bence AK, et al. Among authors: worthen dr. Anticancer Drugs. 2002 Mar;13(3):313-20. doi: 10.1097/00001813-200203000-00013. Anticancer Drugs. 2002. PMID: 11984075

2

L-Canavanine modulates cellular growth, chemosensitivity and P-glycoprotein substrate accumulation in cultured human tumor cell lines.

Worthen DR, Chien L, Tsuboi CP, Mu XY, Bartik MM, Crooks PA. Worthen DR, et al. Cancer Lett. 1998 Oct 23;132(1-2):229-39. doi: 10.1016/s0304-3835(98)00233-x. Cancer Lett. 1998. PMID: 10397478

3

An in vivo evaluation of the antiseizure activity and acute neurotoxicity of agmatine.

Bence AK, Worthen DR, Stables JP, Crooks PA. Bence AK, et al. Among authors: worthen dr. Pharmacol Biochem Behav. 2003 Feb;74(3):771-5. doi: 10.1016/s0091-3057(02)01079-1. Pharmacol Biochem Behav. 2003. PMID: 12543244

4

In vivo evaluation of diaminodiphenyls: anticonvulsant agents with minimal acute neurotoxicity.

Worthen DR, Bence AK, Stables JP, Crooks PA. Worthen DR, et al. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5012-5. doi: 10.1016/j.bmcl.2009.07.059. Epub 2009 Jul 12. Bioorg Med Chem Lett. 2009. PMID: 19632831

5

Structure-activity studies of L-canaline-mediated inhibition of porcine alanine aminotransferase.

Worthen DR, Ratliff DK, Rosenthal GA, Trifonov L, Crooks PA. Worthen DR, et al. Chem Res Toxicol. 1996 Dec;9(8):1293-7. doi: 10.1021/tx9600199. Chem Res Toxicol. 1996. PMID: 8951231

6

Aminoanthraquinones as novel ligands at the polyamine binding site on the N-methyl-D-aspartate receptor complex.

Bence AK, Rogers DT, Worthen DR, Fu M, Littleton JM, Crooks PA. Bence AK, et al. Among authors: worthen dr. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2621-3. doi: 10.1016/s0960-894x(00)00530-8. Bioorg Med Chem Lett. 2000. PMID: 11128637

7

Endogenous indoles as novel polyamine site ligands at the N-methyl-D-aspartate receptor complex.

Worthen DR, Gibson DA, Rogers DT, Bence AK, Fu M, Littleton JM, Crooks PA. Worthen DR, et al. Brain Res. 2001 Feb 2;890(2):343-6. doi: 10.1016/s0006-8993(00)03201-7. Brain Res. 2001. PMID: 11164802

8

The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L.

Worthen DR, Ghosheh OA, Crooks PA. Worthen DR, et al. Anticancer Res. 1998 May-Jun;18(3A):1527-32. Anticancer Res. 1998. PMID: 9673365

9

Regiospecific and conformationally restrained analogs of melphalan and DL-2-NAM-7 and their affinities for the large neutral amino acid transporter (system LAT1) of the blood-brain barrier.

Matharu J, Oki J, Worthen DR, Smith QR, Crooks PA. Matharu J, et al. Among authors: worthen dr. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3688-91. doi: 10.1016/j.bmcl.2010.04.086. Epub 2010 Apr 24. Bioorg Med Chem Lett. 2010. PMID: 20466543 Free PMC article.

10

A unique interaction between polyamine and multidrug resistance (P-glycoprotein) transporters in cultured Chinese hamster ovary cells transfected with mouse mdr-1 gene.

Aziz SM, Worthen DR, Yatin M, Ain KB, Crooks PA. Aziz SM, et al. Among authors: worthen dr. Biochem Pharmacol. 1998 Jul 15;56(2):181-7. doi: 10.1016/s0006-2952(98)00132-4. Biochem Pharmacol. 1998. PMID: 9698071

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