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Identification of hemodynamically stable patients with acute pulmonary embolism at high risk for death: external validation of different models.
Becattini C, Vedovati MC, Colombo S, Vanni S, Abrignani MG, Scardovi AB, Marrazzo A, Borselli M, Barchetti M, Fabbri A, Dentali F, Maggioni AP, Agnelli G, Gulizia MM; COntemporary management of Pulmonary Embolism (COPE) Investigators. Becattini C, et al. J Thromb Haemost. 2024 Sep;22(9):2502-2513. doi: 10.1016/j.jtha.2024.04.025. Epub 2024 May 27. J Thromb Haemost. 2024. PMID: 38810699 Free article.
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA.
Germani S, Van Ho AT, Cherubini A, Varone E, Chernorudskiy A, Renna GM, Fumagalli S, Gobbi M, Lucchetti J, Bolis M, Guarrera L, Craparotta I, Rastelli G, Piccoli G, de Napoli C, Nogara L, Poggio E, Brini M, Cattaneo A, Bachi A, Simmen T, Calì T, Quijano-Roy S, Boncompagni S, Blaauw B, Ferreiro A, Zito E. Germani S, et al. Among authors: rastelli g. Cell Rep Med. 2024 Mar 19;5(3):101439. doi: 10.1016/j.xcrm.2024.101439. Epub 2024 Feb 22. Cell Rep Med. 2024. PMID: 38402623 Free PMC article.
Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction.
Pinzi L, Conze C, Bisi N, Torre GD, Soliman A, Monteiro-Abreu N, Trushina NI, Krusenbaum A, Dolouei MK, Hellwig A, Christodoulou MS, Passarella D, Bakota L, Rastelli G, Brandt R. Pinzi L, et al. Among authors: rastelli g. Nat Commun. 2024 Feb 23;15(1):1679. doi: 10.1038/s41467-024-45851-6. Nat Commun. 2024. PMID: 38396035 Free PMC article.
Loss of calpain 3 dysregulates store-operated calcium entry and its exercise response in mice.
Villani KR, Zhong R, Henley-Beasley CS, Rastelli G, Boncompagni S, Barton ER, Wei-LaPierre L. Villani KR, et al. Among authors: rastelli g. bioRxiv [Preprint]. 2024 Jan 15:2024.01.12.575391. doi: 10.1101/2024.01.12.575391. bioRxiv. 2024. Update in: FASEB J. 2024 Jul 31;38(14):e23825. doi: 10.1096/fj.202400697R PMID: 38293127 Free PMC article. Updated. Preprint.
217 results