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Page 1
Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001.
Nagy MA, Hilgraf R, Mortensen DS, Elsner J, Norris S, Tikhe J, Yoon W, Paisner D, Delgado M, Erdman P, Haelewyn J, Khambatta G, Xu L, Romanow WJ, Condroski K, Bahmanyar S, McCarrick M, Benish B, Blease K, LeBrun L, Moghaddam MF, Apuy J, Canan SS, Bennett BL, Satoh Y. Nagy MA, et al. Among authors: mccarrick m. J Med Chem. 2021 Dec 23;64(24):18193-18208. doi: 10.1021/acs.jmedchem.1c01716. Epub 2021 Dec 13. J Med Chem. 2021. PMID: 34894681
Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.
Plantevin Krenitsky V, Nadolny L, Delgado M, Ayala L, Clareen SS, Hilgraf R, Albers R, Hegde S, D'Sidocky N, Sapienza J, Wright J, McCarrick M, Bahmanyar S, Chamberlain P, Delker SL, Muir J, Giegel D, Xu L, Celeridad M, Lachowitzer J, Bennett B, Moghaddam M, Khatsenko O, Katz J, Fan R, Bai A, Tang Y, Shirley MA, Benish B, Bodine T, Blease K, Raymon H, Cathers BE, Satoh Y. Plantevin Krenitsky V, et al. Among authors: mccarrick m. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1433-8. doi: 10.1016/j.bmcl.2011.12.027. Epub 2011 Dec 10. Bioorg Med Chem Lett. 2012. PMID: 22244937
Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders.
Gomez L, Massari ME, Vickers T, Freestone G, Vernier W, Ly K, Xu R, McCarrick M, Marrone T, Metz M, Yan YG, Yoder ZW, Lemus R, Broadbent NJ, Barido R, Warren N, Schmelzer K, Neul D, Lee D, Andersen CB, Sebring K, Aertgeerts K, Zhou X, Tabatabaei A, Peters M, Breitenbucher JG. Gomez L, et al. Among authors: mccarrick m. J Med Chem. 2017 Mar 9;60(5):2037-2051. doi: 10.1021/acs.jmedchem.6b01793. Epub 2017 Feb 21. J Med Chem. 2017. PMID: 28165743
Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors.
Packard GK, Papa P, Riggs JR, Erdman P, Tehrani L, Robinson D, Harris R, Shevlin G, Perrin-Ninkovic S, Hilgraf R, McCarrick MA, Tran T, Fleming Y, Bai A, Richardson S, Katz J, Tang Y, Leisten J, Moghaddam M, Cathers B, Zhu D, Sakata S. Packard GK, et al. Among authors: mccarrick ma. Bioorg Med Chem Lett. 2012 Jan 1;22(1):747-52. doi: 10.1016/j.bmcl.2011.03.006. Epub 2011 Mar 6. Bioorg Med Chem Lett. 2012. PMID: 22137342
Stimulated Brillouin scatter in a magnetized ionospheric plasma.
Bernhardt PA, Selcher CA, Lehmberg RH, Rodriguez SP, Thomason JF, Groves KM, McCarrick MJ, Frazer GJ. Bernhardt PA, et al. Among authors: mccarrick mj. Phys Rev Lett. 2010 Apr 23;104(16):165004. doi: 10.1103/PhysRevLett.104.165004. Epub 2010 Apr 22. Phys Rev Lett. 2010. PMID: 20482059
Radio pumping of ionospheric plasma with orbital angular momentum.
Leyser TB, Norin L, McCarrick M, Pedersen TR, Gustavsson B. Leyser TB, et al. Among authors: mccarrick m. Phys Rev Lett. 2009 Feb 13;102(6):065004. doi: 10.1103/PhysRevLett.102.065004. Epub 2009 Feb 12. Phys Rev Lett. 2009. PMID: 19257597
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