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How T cells use LFA-1 to attach and migrate.
Hogg N, Smith A, McDowall A, Giles K, Stanley P, Laschinger M, Henderson R. Hogg N, et al. Among authors: smith a. Immunol Lett. 2004 Mar 29;92(1-2):51-4. doi: 10.1016/j.imlet.2003.10.014. Immunol Lett. 2004. PMID: 15081527 Review.
Importance of integrin LFA-1 deactivation for the generation of immune responses.
Semmrich M, Smith A, Feterowski C, Beer S, Engelhardt B, Busch DH, Bartsch B, Laschinger M, Hogg N, Pfeffer K, Holzmann B. Semmrich M, et al. Among authors: smith a. J Exp Med. 2005 Jun 20;201(12):1987-98. doi: 10.1084/jem.20041850. Epub 2005 Jun 13. J Exp Med. 2005. PMID: 15955836 Free PMC article.
TCR/CD3 mediated stop-signal is decoupled in T-cells from Ctla4 deficient mice.
Downey J, Smith A, Schneider H, Hogg N, Rudd CE. Downey J, et al. Among authors: smith a. Immunol Lett. 2008 Jan 15;115(1):70-2. doi: 10.1016/j.imlet.2007.09.004. Epub 2007 Oct 5. Immunol Lett. 2008. PMID: 17964663 Free PMC article.
CTLA-4 is a co-receptor that plays a pivotal role in regulating the threshold for T-cell activation. We recently reported that CTLA-4 ligation can over-ride the stop-signal induced by anti-CD3 ligation [Schneider H, Downey J, Smith A, Zinselmeyer BH, R …
CTLA-4 is a co-receptor that plays a pivotal role in regulating the threshold for T-cell activation. We recently reported that …
Reversal of the TCR stop signal by CTLA-4.
Schneider H, Downey J, Smith A, Zinselmeyer BH, Rush C, Brewer JM, Wei B, Hogg N, Garside P, Rudd CE. Schneider H, et al. Among authors: smith a. Science. 2006 Sep 29;313(5795):1972-5. doi: 10.1126/science.1131078. Epub 2006 Aug 24. Science. 2006. PMID: 16931720
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