Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity.
Pelkonen P, Lang MA, Negishi M, Wild CP, Juvonen RO.
Pelkonen P, et al. Among authors: juvonen ro.
Chem Res Toxicol. 1997 Jan;10(1):85-90. doi: 10.1021/tx960078m.
Chem Res Toxicol. 1997.
PMID: 9074807
Among members of the mouse cytochrome P450 2A family, P450 2A5 is the best catalyst of aflatoxin B1 (AFB1) oxidation to its 8,9-epoxide (Pelkonen, P., Lang, M., Wild, C. P., Negishi, M., and Juvonen, R. O. (1994) Eur. J. Pharmacol., Environ. Toxicol. Pharmacol. Sect …
Among members of the mouse cytochrome P450 2A family, P450 2A5 is the best catalyst of aflatoxin B1 (AFB1) oxidation to its 8,9-epoxide (Pel …