Knapp S - Search Results

1

High-throughput NMR-based screening with competition binding experiments.

Dalvit C, Flocco M, Knapp S, Mostardini M, Perego R, Stockman BJ, Veronesi M, Varasi M. Dalvit C, et al. Among authors: knapp s. J Am Chem Soc. 2002 Jul 3;124(26):7702-9. doi: 10.1021/ja020174b. J Am Chem Soc. 2002. PMID: 12083923

2

NMR-Based screening with competition water-ligand observed via gradient spectroscopy experiments: detection of high-affinity ligands.

Dalvit C, Fasolini M, Flocco M, Knapp S, Pevarello P, Veronesi M. Dalvit C, et al. Among authors: knapp s. J Med Chem. 2002 Jun 6;45(12):2610-4. doi: 10.1021/jm011122k. J Med Chem. 2002. PMID: 12036370

3

Hot spots in Tcf4 for the interaction with beta-catenin.

Fasolini M, Wu X, Flocco M, Trosset JY, Oppermann U, Knapp S. Fasolini M, et al. Among authors: knapp s. J Biol Chem. 2003 Jun 6;278(23):21092-8. doi: 10.1074/jbc.M301781200. Epub 2003 Mar 25. J Biol Chem. 2003. PMID: 12657632 Free article.

4

Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a.

Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Schiering N, et al. Among authors: knapp s. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. doi: 10.1073/pnas.1734128100. Epub 2003 Oct 14. Proc Natl Acad Sci U S A. 2003. PMID: 14559966 Free PMC article.

5

Regulation of the wild-type and Y1235D mutant Met kinase activation.

Cristiani C, Rusconi L, Perego R, Schiering N, Kalisz HM, Knapp S, Isacchi A. Cristiani C, et al. Among authors: knapp s. Biochemistry. 2005 Nov 1;44(43):14110-9. doi: 10.1021/bi051242k. Biochemistry. 2005. PMID: 16245927

6

Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening.

Trosset JY, Dalvit C, Knapp S, Fasolini M, Veronesi M, Mantegani S, Gianellini LM, Catana C, Sundström M, Stouten PF, Moll JK. Trosset JY, et al. Among authors: knapp s. Proteins. 2006 Jul 1;64(1):60-7. doi: 10.1002/prot.20955. Proteins. 2006. PMID: 16568448

7

¹⁹ F NMR isotropic chemical shift for efficient screening of fluorinated fragments which are racemates and/or display multiple conformers.

Dalvit C, Knapp S. Dalvit C, et al. Among authors: knapp s. Magn Reson Chem. 2017 Dec;55(12):1091-1095. doi: 10.1002/mrc.4640. Epub 2017 Aug 24. Magn Reson Chem. 2017. PMID: 28762528

8

The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes.

Knapp S, Müller S, Digilio G, Bonaldi T, Bianchi ME, Musco G. Knapp S, et al. Biochemistry. 2004 Sep 28;43(38):11992-7. doi: 10.1021/bi049364k. Biochemistry. 2004. PMID: 15379539

9

Binding Kinetics Survey of the Drugged Kinome.

Georgi V, Schiele F, Berger BT, Steffen A, Marin Zapata PA, Briem H, Menz S, Preusse C, Vasta JD, Robers MB, Brands M, Knapp S, Fernández-Montalván A. Georgi V, et al. Among authors: knapp s. J Am Chem Soc. 2018 Nov 21;140(46):15774-15782. doi: 10.1021/jacs.8b08048. Epub 2018 Nov 6. J Am Chem Soc. 2018. PMID: 30362749

10

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains.

Hay DA, Fedorov O, Martin S, Singleton DC, Tallant C, Wells C, Picaud S, Philpott M, Monteiro OP, Rogers CM, Conway SJ, Rooney TP, Tumber A, Yapp C, Filippakopoulos P, Bunnage ME, Müller S, Knapp S, Schofield CJ, Brennan PE. Hay DA, et al. Among authors: knapp s. J Am Chem Soc. 2014 Jul 2;136(26):9308-19. doi: 10.1021/ja412434f. Epub 2014 Jun 19. J Am Chem Soc. 2014. PMID: 24946055 Free PMC article.

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