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Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.
Straub RE, Jiang Y, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, Cesare AJ, Gibberman A, Wang X, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: maclean cj. Am J Hum Genet. 2002 Aug;71(2):337-48. doi: 10.1086/341750. Epub 2002 Jul 3. Am J Hum Genet. 2002. PMID: 12098102 Free PMC article.
A schizophrenia locus may be located in region 10p15-p11.
Straub RE, MacLean CJ, Martin RB, Ma Y, Myakishev MV, Harris-Kerr C, Webb BT, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: maclean cj. Am J Med Genet. 1998 Jul 10;81(4):296-301. doi: 10.1002/(sici)1096-8628(19980710)81:4<296::aid-ajmg4>3.0.co;2-s. Am J Med Genet. 1998. PMID: 9674974
The trimmed-haplotype test for linkage disequilibrium.
MacLean CJ, Martin RB, Sham PC, Wang H, Straub RE, Kendler KS. MacLean CJ, et al. Am J Hum Genet. 2000 Mar;66(3):1062-75. doi: 10.1086/302796. Am J Hum Genet. 2000. PMID: 10712218 Free PMC article.
Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes.
Straub RE, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: maclean cj. Mol Psychiatry. 2002;7(6):542-59. doi: 10.1038/sj.mp.4001051. Mol Psychiatry. 2002. PMID: 12140777
138 results