Eckner RJ - Search Results

1

Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.

Snow RJ, Cardozo MG, Morwick TM, Busacca CA, Dong Y, Eckner RJ, Jacober S, Jakes S, Kapadia S, Lukas S, Panzenbeck M, Peet GW, Peterson JD, Prokopowicz AS 3rd, Sellati R, Tolbert RM, Tschantz MA, Moss N. Snow RJ, et al. Among authors: eckner rj. J Med Chem. 2002 Aug 1;45(16):3394-405. doi: 10.1021/jm020113o. J Med Chem. 2002. PMID: 12139450

2

Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.

Goldberg DR, Butz T, Cardozo MG, Eckner RJ, Hammach A, Huang J, Jakes S, Kapadia S, Kashem M, Lukas S, Morwick TM, Panzenbeck M, Patel U, Pav S, Peet GW, Peterson JD, Prokopowicz AS 3rd, Snow RJ, Sellati R, Takahashi H, Tan J, Tschantz MA, Wang XJ, Wang Y, Wolak J, Xiong P, Moss N. Goldberg DR, et al. Among authors: eckner rj. J Med Chem. 2003 Apr 10;46(8):1337-49. doi: 10.1021/jm020446l. J Med Chem. 2003. PMID: 12672234

3

Non-sialate inhibitor of influenza A/WSN/33 neuraminidase.

Wu JC, Peet GW, Coutts SJ, Eckner RJ, Griffin JA, Farina PR. Wu JC, et al. Among authors: eckner rj. Biochemistry. 1995 May 30;34(21):7154-60. doi: 10.1021/bi00021a029. Biochemistry. 1995. PMID: 7539292

4

Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by the dipyridodiazepinone BI-RG-587.

Koup RA, Merluzzi VJ, Hargrave KD, Adams J, Grozinger K, Eckner RJ, Sullivan JL. Koup RA, et al. Among authors: eckner rj. J Infect Dis. 1991 May;163(5):966-70. doi: 10.1093/infdis/163.5.966. J Infect Dis. 1991. PMID: 1708400

5

BI-RG-587 is active against zidovudine-resistant human immunodeficiency virus type 1 and synergistic with zidovudine.

Richman D, Rosenthal AS, Skoog M, Eckner RJ, Chou TC, Sabo JP, Merluzzi VJ. Richman D, et al. Among authors: eckner rj. Antimicrob Agents Chemother. 1991 Feb;35(2):305-8. doi: 10.1128/AAC.35.2.305. Antimicrob Agents Chemother. 1991. PMID: 1708976 Free PMC article.

6

Natural killer cell suppression of Friend virus-induced preleukemic hemopoietic stem cells.

Eckner RJ, Bennett M, Hettrick KL, Seidler C. Eckner RJ, et al. J Virol. 1987 Aug;61(8):2631-8. doi: 10.1128/JVI.61.8.2631-2638.1987. J Virol. 1987. PMID: 3474419 Free PMC article.

7

Friend virus-infected long-term bone marrow cultures produce colony stimulating factor dependent and independent granulocyte-macrophage progenitor cells for over four years in vitro.

Greenberger JS, Daugherty C, Sakakeeny MA, Braun J, Pierce JH, Eckner RJ, FitzGerald TJ. Greenberger JS, et al. Among authors: eckner rj. Leuk Res. 1987;11(1):51-61. doi: 10.1016/0145-2126(87)90105-6. Leuk Res. 1987. PMID: 3492638

8

Expression of a retrovirus encoding human HPRT in mice.

Miller AD, Eckner RJ, Jolly DJ, Friedmann T, Verma IM. Miller AD, et al. Among authors: eckner rj. Science. 1984 Aug 10;225(4662):630-2. doi: 10.1126/science.6377498. Science. 1984. PMID: 6377498

9

Interleukin 3-dependent hematopoietic progenitor cell lines.

Greenberger JS, Eckner RJ, Sakakeeny M, Marks P, Reid D, Nabel G, Hapel A, Ihle JN, Humphries KC. Greenberger JS, et al. Among authors: eckner rj. Fed Proc. 1983 Jul;42(10):2762-71. Fed Proc. 1983. PMID: 6305732

10

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.

Greenberger JS, Sakakeeny MA, Humphries RK, Eaves CJ, Eckner RJ. Greenberger JS, et al. Among authors: eckner rj. Proc Natl Acad Sci U S A. 1983 May;80(10):2931-5. doi: 10.1073/pnas.80.10.2931. Proc Natl Acad Sci U S A. 1983. PMID: 6574462 Free PMC article.

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