Peet GW - Search Results

1

Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.

Snow RJ, Cardozo MG, Morwick TM, Busacca CA, Dong Y, Eckner RJ, Jacober S, Jakes S, Kapadia S, Lukas S, Panzenbeck M, Peet GW, Peterson JD, Prokopowicz AS 3rd, Sellati R, Tolbert RM, Tschantz MA, Moss N. Snow RJ, et al. Among authors: peet gw. J Med Chem. 2002 Aug 1;45(16):3394-405. doi: 10.1021/jm020113o. J Med Chem. 2002. PMID: 12139450

2

Non-sialate inhibitor of influenza A/WSN/33 neuraminidase.

Wu JC, Peet GW, Coutts SJ, Eckner RJ, Griffin JA, Farina PR. Wu JC, et al. Among authors: peet gw. Biochemistry. 1995 May 30;34(21):7154-60. doi: 10.1021/bi00021a029. Biochemistry. 1995. PMID: 7539292

3

Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha.

Li J, Peet GW, Pullen SS, Schembri-King J, Warren TC, Marcu KB, Kehry MR, Barton R, Jakes S. Li J, et al. Among authors: peet gw. J Biol Chem. 1998 Nov 13;273(46):30736-41. doi: 10.1074/jbc.273.46.30736. J Biol Chem. 1998. PMID: 9804849 Free article.

4

Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.

Goldberg DR, Butz T, Cardozo MG, Eckner RJ, Hammach A, Huang J, Jakes S, Kapadia S, Kashem M, Lukas S, Morwick TM, Panzenbeck M, Patel U, Pav S, Peet GW, Peterson JD, Prokopowicz AS 3rd, Snow RJ, Sellati R, Takahashi H, Tan J, Tschantz MA, Wang XJ, Wang Y, Wolak J, Xiong P, Moss N. Goldberg DR, et al. Among authors: peet gw. J Med Chem. 2003 Apr 10;46(8):1337-49. doi: 10.1021/jm020446l. J Med Chem. 2003. PMID: 12672234

5

The kinetics of binding to p38MAP kinase by analogues of BIRB 796.

Regan J, Pargellis CA, Cirillo PF, Gilmore T, Hickey ER, Peet GW, Proto A, Swinamer A, Moss N. Regan J, et al. Among authors: peet gw. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3101-4. doi: 10.1016/s0960-894x(03)00656-5. Bioorg Med Chem Lett. 2003. PMID: 12941343

6

Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors.

Kroe RR, Regan J, Proto A, Peet GW, Roy T, Landro LD, Fuschetto NG, Pargellis CA, Ingraham RH. Kroe RR, et al. Among authors: peet gw. J Med Chem. 2003 Oct 23;46(22):4669-75. doi: 10.1021/jm030120s. J Med Chem. 2003. PMID: 14561086

7

Catalysis and function of the p38 alpha.MK2a signaling complex.

Lukas SM, Kroe RR, Wildeson J, Peet GW, Frego L, Davidson W, Ingraham RH, Pargellis CA, Labadia ME, Werneburg BG. Lukas SM, et al. Among authors: peet gw. Biochemistry. 2004 Aug 10;43(31):9950-60. doi: 10.1021/bi049508v. Biochemistry. 2004. PMID: 15287722

8

Discovery and characterization of a substrate selective p38alpha inhibitor.

Davidson W, Frego L, Peet GW, Kroe RR, Labadia ME, Lukas SM, Snow RJ, Jakes S, Grygon CA, Pargellis C, Werneburg BG. Davidson W, et al. Among authors: peet gw. Biochemistry. 2004 Sep 21;43(37):11658-71. doi: 10.1021/bi0495073. Biochemistry. 2004. PMID: 15362850

9

The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.

Wu JP, Wang J, Abeywardane A, Andersen D, Emmanuel M, Gautschi E, Goldberg DR, Kashem MA, Lukas S, Mao W, Martin L, Morwick T, Moss N, Pargellis C, Patel UR, Patnaude L, Peet GW, Skow D, Snow RJ, Ward Y, Werneburg B, White A. Wu JP, et al. Among authors: peet gw. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4664-9. doi: 10.1016/j.bmcl.2007.05.101. Epub 2007 Jun 7. Bioorg Med Chem Lett. 2007. PMID: 17576063

10

The discovery of thienopyridine analogues as potent IkappaB kinase beta inhibitors. Part II.

Wu JP, Fleck R, Brickwood J, Capolino A, Catron K, Chen Z, Cywin C, Emeigh J, Foerst M, Ginn J, Hrapchak M, Hickey E, Hao MH, Kashem M, Li J, Liu W, Morwick T, Nelson R, Marshall D, Martin L, Nemoto P, Potocki I, Liuzzi M, Peet GW, Scouten E, Stefany D, Turner M, Weldon S, Zimmitti C, Spero D, Kelly TA. Wu JP, et al. Among authors: peet gw. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5547-51. doi: 10.1016/j.bmcl.2009.08.054. Epub 2009 Aug 15. Bioorg Med Chem Lett. 2009. PMID: 19716697

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