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Page 1
Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes.
Straub RE, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: harris kerr c. Mol Psychiatry. 2002;7(6):542-59. doi: 10.1038/sj.mp.4001051. Mol Psychiatry. 2002. PMID: 12140777
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.
Straub RE, Jiang Y, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, Cesare AJ, Gibberman A, Wang X, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: harris kerr c. Am J Hum Genet. 2002 Aug;71(2):337-48. doi: 10.1086/341750. Epub 2002 Jul 3. Am J Hum Genet. 2002. PMID: 12098102 Free PMC article.
A schizophrenia locus may be located in region 10p15-p11.
Straub RE, MacLean CJ, Martin RB, Ma Y, Myakishev MV, Harris-Kerr C, Webb BT, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: harris kerr c. Am J Med Genet. 1998 Jul 10;81(4):296-301. doi: 10.1002/(sici)1096-8628(19980710)81:4<296::aid-ajmg4>3.0.co;2-s. Am J Med Genet. 1998. PMID: 9674974
Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study.
Straub RE, Sullivan PF, Ma Y, Myakishev MV, Harris-Kerr C, Wormley B, Kadambi B, Sadek H, Silverman MA, Webb BT, Neale MC, Bulik CM, Joyce PR, Kendler KS. Straub RE, et al. Among authors: harris kerr c. Mol Psychiatry. 1999 Mar;4(2):129-44. doi: 10.1038/sj.mp.4000518. Mol Psychiatry. 1999. PMID: 10208445
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing.
Kapplinger JD, Tester DJ, Alders M, Benito B, Berthet M, Brugada J, Brugada P, Fressart V, Guerchicoff A, Harris-Kerr C, Kamakura S, Kyndt F, Koopmann TT, Miyamoto Y, Pfeiffer R, Pollevick GD, Probst V, Zumhagen S, Vatta M, Towbin JA, Shimizu W, Schulze-Bahr E, Antzelevitch C, Salisbury BA, Guicheney P, Wilde AA, Brugada R, Schott JJ, Ackerman MJ. Kapplinger JD, et al. Among authors: harris kerr c. Heart Rhythm. 2010 Jan;7(1):33-46. doi: 10.1016/j.hrthm.2009.09.069. Epub 2009 Oct 8. Heart Rhythm. 2010. PMID: 20129283 Free PMC article.
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