Hutton M - Search Results

1

The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons.

Utton MA, Connell J, Asuni AA, van Slegtenhorst M, Hutton M, de Silva R, Lees AJ, Miller CC, Anderton BH. Utton MA, et al. Among authors: hutton m. J Neurosci. 2002 Aug 1;22(15):6394-400. doi: 10.1523/JNEUROSCI.22-15-06394.2002. J Neurosci. 2002. PMID: 12151518 Free PMC article.

2

Tau proteins with frontotemporal dementia-17 mutations have both altered expression levels and phosphorylation profiles in differentiated neuroblastoma cells.

Mack TG, Dayanandan R, Van Slegtenhorst M, Whone A, Hutton M, Lovestone S, Anderton BH. Mack TG, et al. Among authors: hutton m. Neuroscience. 2001;108(4):701-12. doi: 10.1016/s0306-4522(01)00434-1. Neuroscience. 2001. PMID: 11738505

3

Sites of phosphorylation in tau and factors affecting their regulation.

Anderton BH, Betts J, Blackstock WP, Brion JP, Chapman S, Connell J, Dayanandan R, Gallo JM, Gibb G, Hanger DP, Hutton M, Kardalinou E, Leroy K, Lovestone S, Mack T, Reynolds CH, Van Slegtenhorst M. Anderton BH, et al. Among authors: hutton m. Biochem Soc Symp. 2001;(67):73-80. doi: 10.1042/bss0670073. Biochem Soc Symp. 2001. PMID: 11447841

4

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation.

Dayanandan R, Van Slegtenhorst M, Mack TG, Ko L, Yen SH, Leroy K, Brion JP, Anderton BH, Hutton M, Lovestone S. Dayanandan R, et al. Among authors: hutton m. FEBS Lett. 1999 Mar 12;446(2-3):228-32. doi: 10.1016/s0014-5793(99)00222-7. FEBS Lett. 1999. PMID: 10100846 Free article.

5

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies.

Rodriguez-Martin T, Garcia-Blanco MA, Mansfield SG, Grover AC, Hutton M, Yu Q, Zhou J, Anderton BH, Gallo JM. Rodriguez-Martin T, et al. Among authors: hutton m. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15659-64. doi: 10.1073/pnas.0503150102. Epub 2005 Oct 17. Proc Natl Acad Sci U S A. 2005. PMID: 16230627 Free PMC article.

6

Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes.

Connell JW, Gibb GM, Betts JC, Blackstock WP, Gallo J, Lovestone S, Hutton M, Anderton BH. Connell JW, et al. Among authors: hutton m. FEBS Lett. 2001 Mar 23;493(1):40-4. doi: 10.1016/s0014-5793(01)02267-0. FEBS Lett. 2001. PMID: 11278002 Free article.

7

Missense tau mutations identified in FTDP-17 have a small effect on tau-microtubule interactions.

DeTure M, Ko LW, Yen S, Nacharaju P, Easson C, Lewis J, van Slegtenhorst M, Hutton M, Yen SH. DeTure M, et al. Among authors: hutton m. Brain Res. 2000 Jan 17;853(1):5-14. doi: 10.1016/s0006-8993(99)02124-1. Brain Res. 2000. PMID: 10627302

8

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy.

Hogg M, Grujic ZM, Baker M, Demirci S, Guillozet AL, Sweet AP, Herzog LL, Weintraub S, Mesulam MM, LaPointe NE, Gamblin TC, Berry RW, Binder LI, de Silva R, Lees A, Espinoza M, Davies P, Grover A, Sahara N, Ishizawa T, Dickson D, Yen SH, Hutton M, Bigio EH. Hogg M, et al. Among authors: hutton m. Acta Neuropathol. 2003 Oct;106(4):323-36. doi: 10.1007/s00401-003-0734-x. Epub 2003 Jul 19. Acta Neuropathol. 2003. PMID: 12883828

9

The molecular genetics of the tauopathies.

van Slegtenhorst M, Lewis J, Hutton M. van Slegtenhorst M, et al. Among authors: hutton m. Exp Gerontol. 2000 Jul;35(4):461-71. doi: 10.1016/s0531-5565(00)00114-5. Exp Gerontol. 2000. PMID: 10959034 Review.

10

Analysis of tau haplotypes in Pick's disease.

Morris HR, Baker M, Yasojima K, Houlden H, Khan MN, Wood NW, Hardy J, Grossman M, Trojanowski J, Revesz T, Bigio EH, Bergeron C, Janssen JC, McGeer PL, Rossor MN, Lees AJ, Lantos PL, Hutton M. Morris HR, et al. Among authors: hutton m. Neurology. 2002 Aug 13;59(3):443-5. doi: 10.1212/wnl.59.3.443. Neurology. 2002. PMID: 12177383

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