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Page 1
Detecting recent positive selection in the human genome from haplotype structure.
Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, Schaffner SF, Gabriel SB, Platko JV, Patterson NJ, McDonald GJ, Ackerman HC, Campbell SJ, Altshuler D, Cooper R, Kwiatkowski D, Ward R, Lander ES. Sabeti PC, et al. Among authors: higgins jm. Nature. 2002 Oct 24;419(6909):832-7. doi: 10.1038/nature01140. Epub 2002 Oct 9. Nature. 2002. PMID: 12397357
The structure of haplotype blocks in the human genome.
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D. Gabriel SB, et al. Among authors: higgins j. Science. 2002 Jun 21;296(5576):2225-9. doi: 10.1126/science.1069424. Epub 2002 May 23. Science. 2002. PMID: 12029063
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms.
Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, Rogers J, Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B, Cook L, Davenport R, Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B, Schaffner S, Van Etten WJ, Reich D, Higgins J, Daly MJ, Blumenstiel B, Baldwin J, Stange-Thomann N, Zody MC, Linton L, Lander ES, Altshuler D; International SNP Map Working Group. Sachidanandam R, et al. Among authors: higgins j. Nature. 2001 Feb 15;409(6822):928-33. doi: 10.1038/35057149. Nature. 2001. PMID: 11237013
Monocyte Anisocytosis is Associated with Sepsis in Children with Suspected Infection.
Yonker LM, Badaki-Makun O, Alvarez-Carcamo B, Cross C, Okuducu Y, Appleman L, Greatorex J, Onu RE, Santos C, Petherbridge R, Foy BH, Cereaga D, Naiman M, Castro I, Haller L, Guthrie LB, Higgins JM, Lewandrowski KB, Irimia D. Yonker LM, et al. Among authors: higgins jm. Shock. 2024 Oct 11. doi: 10.1097/SHK.0000000000002502. Online ahead of print. Shock. 2024. PMID: 39749928
Haematological setpoints are a stable and patient-specific deep phenotype.
Foy BH, Petherbridge R, Roth MT, Zhang C, De Souza DC, Mow C, Patel HR, Patel CH, Ho SN, Lam E, Powe CE, Hasserjian RP, Karczewski KJ, Tozzo V, Higgins JM. Foy BH, et al. Among authors: higgins jm. Nature. 2025 Jan;637(8045):430-438. doi: 10.1038/s41586-024-08264-5. Epub 2024 Dec 11. Nature. 2025. PMID: 39663453
164 results