O'Brien JA - Search Results

1

A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors.

Lemaire W, O'Brien JA, Burno M, Chaudhary AG, Dean DC, Williams PD, Freidinger RM, Pettibone DJ, Williams DL Jr. Lemaire W, et al. Eur J Pharmacol. 2002 Aug 16;450(1):19-28. doi: 10.1016/s0014-2999(02)02048-4. Eur J Pharmacol. 2002. PMID: 12176104

2

Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells.

Jasper JR, Harrell CM, O'Brien JA, Pettibone DJ. Jasper JR, et al. Life Sci. 1995;57(24):2253-61. doi: 10.1016/0024-3205(95)02218-8. Life Sci. 1995. PMID: 7475979

3

Pharmacology of L-754,142, a highly potent, orally active, nonpeptidyl endothelin antagonist.

Williams DL Jr, Murphy KL, Nolan NA, O'Brien JA, Pettibone DJ, Kivlighn SD, Krause SM, Lis EV Jr, Zingaro GJ, Gabel RA, et al. Williams DL Jr, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1518-26. J Pharmacol Exp Ther. 1995. PMID: 8531124

4

Pharmacology of L-744,453, a novel nonpeptidyl endothelin antagonist.

Williams DL Jr, Murphy KL, Nolan NA, O'Brien JA, Lis EV Jr, Pettibone DJ, Clineschmidt BV, Krause SM, Veber DF, Naylor EM, Chakravarty PK, Walsh TF, Dhanoa DM, Chen A, Bagley SW, Fitch KJ, Greenlee WJ. Williams DL Jr, et al. Life Sci. 1996;58(14):1149-57. doi: 10.1016/0024-3205(96)00073-2. Life Sci. 1996. PMID: 8614266

5

Progress in the development of oxytocin antagonists for use in preterm labor.

Pettibone DJ, Guidotti M, Harrell CM, Jasper JR, Lis EV, O'Brien JA, Reiss DR, Woyden CJ, Bock MG, Evans BE, et al. Pettibone DJ, et al. Adv Exp Med Biol. 1995;395:601-12. Adv Exp Med Biol. 1995. PMID: 8714024 Review.

6

Pharmacological properties of J-104132 (L-753,037), a potent, orally active, mixed ETA/ETB endothelin receptor antagonist.

Nishikibe M, Ohta H, Okada M, Ishikawa K, Hayama T, Fukuroda T, Noguchi K, Saito M, Kanoh T, Ozaki S, Kamei T, Hara K, William D, Kivlighn S, Krause S, Gabel R, Zingaro G, Nolan N, O'Brien J, Clayton F, Lynch J, Pettibone D, Siegl P. Nishikibe M, et al. J Pharmacol Exp Ther. 1999 Jun;289(3):1262-70. J Pharmacol Exp Ther. 1999. PMID: 10336515

7

Molecular cloning and pharmacological characterization of the canine B1 and B2 bradykinin receptors.

Hess JF, Hey PJ, Chen TB, O'Brien J, Omalley SS, Pettibone DJ, Chang RS. Hess JF, et al. Biol Chem. 2001 Jan;382(1):123-9. doi: 10.1515/BC.2001.018. Biol Chem. 2001. PMID: 11258662

8

A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.

O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn PJ, Williams DL Jr. O'Brien JA, et al. Mol Pharmacol. 2003 Sep;64(3):731-40. doi: 10.1124/mol.64.3.731. Mol Pharmacol. 2003. PMID: 12920211

9

Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment.

Marino MJ, Williams DL Jr, O'Brien JA, Valenti O, McDonald TP, Clements MK, Wang R, DiLella AG, Hess JF, Kinney GG, Conn PJ. Marino MJ, et al. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13668-73. doi: 10.1073/pnas.1835724100. Epub 2003 Oct 30. Proc Natl Acad Sci U S A. 2003. PMID: 14593202 Free PMC article.

10

Modulation of inhibitory transmission in the rat globus pallidus by activation of mGluR4.

Marino MJ, Valenti O, O'Brien JA, Williams DL Jr, Conn PJ. Marino MJ, et al. Ann N Y Acad Sci. 2003 Nov;1003:435-7. doi: 10.1196/annals.1300.045. Ann N Y Acad Sci. 2003. PMID: 14684481 No abstract available.

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