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The proximate carcinogen trans-3,4-dihydroxy-3,4-dihydro-dibenz[c,h]acridine is oxidized stereoselectively and regioselectively by cytochrome 1A1, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats.
Adams JD Jr, Sayer JM, Chadha A, Shirai N, Lehr RE, Kumar S, Jerina DM. Adams JD Jr, et al. Among authors: shirai n. Chem Biol Interact. 1999 Sep 30;122(2):117-35. doi: 10.1016/s0009-2797(99)00116-7. Chem Biol Interact. 1999. PMID: 10528997
344 results