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TnpB structure reveals minimal functional core of Cas12 nuclease family.
Sasnauskas G, Tamulaitiene G, Druteika G, Carabias A, Silanskas A, Kazlauskas D, Venclovas Č, Montoya G, Karvelis T, Siksnys V. Sasnauskas G, et al. Among authors: venclovas c. Nature. 2023 Apr;616(7956):384-389. doi: 10.1038/s41586-023-05826-x. Epub 2023 Apr 5. Nature. 2023. PMID: 37020015
The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Manakova E, Golovinas E, Pocevičiūtė R, Sasnauskas G, Silanskas A, Rutkauskas D, Jankunec M, Zagorskaitė E, Jurgelaitis E, Grybauskas A, Venclovas Č, Zaremba M. Manakova E, et al. Among authors: venclovas c. Nucleic Acids Res. 2024 Mar 21;52(5):2530-2545. doi: 10.1093/nar/gkad1241. Nucleic Acids Res. 2024. PMID: 38197228 Free PMC article.
RecA-NT homology motif in ImuB is essential for mycobacterial ImuA'-ImuB protein interaction and mutasome function.
Santos JA, Timinskas K, Lamers MH, Venclovas Č, Warner DF, Gessner SJ. Santos JA, et al. Among authors: venclovas c. bioRxiv [Preprint]. 2023 Mar 28:2023.03.28.534377. doi: 10.1101/2023.03.28.534377. bioRxiv. 2023. Update in: J Biol Chem. 2024 Dec 18:108108. doi: 10.1016/j.jbc.2024.108108 PMID: 37034714 Free PMC article. Updated. Preprint.
103 results